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Article
PGC-1α is associated with C2C12 Myoblast differentiation
PGC-1α has been implicated as an important mediator of functional capacity of skeletal muscle. However, the role of PGC-1α in myoblast differentiation remains unexplored. In the present study, we observed a si...
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Article
Bevacizumab cured age-related macular degeneration (AMD) via down-regulate TLR2 pathway
AMD is the main cause of visual impairment in people over 50 years of age and the most common cause of blindness. In recent years, the use of bevacizumab to treat neovascular AMD has become a preferred treatme...
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Article
Acute and joint toxicity of twelve substituted benzene compounds to Propsilocerus akamusi Tokunaga
This study investigated the toxic effects of 12 substituted benzenes exposed to Propsilocerus akamusi larvae singly and as mixtures. Their toxicities were quantified in terms of median effective concentration (EC
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Article
Cloning and characterization of a cold inducible Pal promoter from Fagopyrum tataricum
Phenylalanine ammonia-lyase (PAL) catalyzes the first reaction in biosynthesis pathway of flavonoids and plays an important role in plant stress resistance. In this study, the 5’ flanking region of phenylalani...
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Article
Effect of nitrite exposure on metabolic response in the freshwater prawn Macrobrachium nipponense
The metabolic response of the freshwater prawn, Macrobrachium nipponense to nitrite toxicity was evaluated. The prawns were exposed to 0, 1, 2, 3 and 4 mg L−1 NO2-N concentrations for 48 h. The metabolic paramete...
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Article
Erratum to Central European Journal of Biology, Volume 8, Issue 11
Paper by Li Li Huijuan Wu, Jialin Qian, Mingzhen Li, Yue Li, Baoming Li et al. “Decreased Na+/K+ ATPase α1 (ATP1A1) gene expression in major depression patients’ peripheral blood” in Voulme 8, Issue 11, 1077-1...
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Article
Decreased Na+/K+ ATPase α1 (ATP1A1) gene expression in major depression patients’ peripheral blood
Major depression affects the central nervous system and thereafter the autonomic nervous system, immune system, and endocrine system. Na+/K+ ATPase, as a major mediator of cellular transmembrane ionic gradient...
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Article
Long-term melatonin administration improves glucose homeostasis and insulin resistance state in high-fat-diet fed rats
Emerging evidence support an important role of reactive oxygen species in various forms of insulin resistance. It is identified that melatonin has antioxidant properties and prevents toxic effects of reactive ...
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Article
Natural rules for Arabidopsis thaliana pre-mRNA splicing site selection
The accurate prediction of plant pre-mRNA splicing sites has been studied extensively. The rules for plant pre-mRNA splicing still remain unknown. This study, based on confirmed sequence data, systematically a...
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Article
The evolutionarily conserved MOS4-associated complex
Recent work in plant immunity has shown that MOS4, a known intermediate in R protein mediated resistance, is a core member of the nuclear MOS4-associated complex (MAC). This complex is highly conserved in euka...
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Article
Biochemical responses in gills of rainbow trout exposed to propiconazole
The aim of this study is to investigate the toxic effect of PCZ, a triazole fungicide commonly present in surface and ground water, on the ROS defense system and Na+-K+-ATPase in gills of rainbow trout exposed to...
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Article
Comparison of antioxidant capacity and phenolic compounds of berries, chokecherry and seabuckthorn
Antioxidant capacity and phenolic compounds (phenolic acids and anthocyanins) of four berry fruits (strawberry, Saskatoon berry, raspberry and wild blueberry), chokecherry and seabuckthorn were compared in the...
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Protocol
Mammalian Two-Hybrid Assay for Detecting Protein-Protein Interactions in Vivo
The mammalian two-hybrid system is a very powerful tool to investigate protein-protein interactions in terms of functional domains and identify potential binding ligands and partners of a protein. Compared wit...
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Protocol
Protein Chip for Detection of DNA Mutations
A large number of human genetic diseases, bacterial drug resistances, and single-nucleotide polymorphisms are caused by gene mutations. Rapid and high-throughput mutation detection methods are urgently demande...
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Protocol
Nanotechnology
Microarrays are important tools for high-throughput analysis of biomolecules. The use of microarrays for parallel screening of nucleic acid and protein profiles has become an industry standard. A few limitatio...
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Article
A correlation between radiation sensitivity and initial chromatid breaks in cancer cell lines revealed by Calyculin A-induced premature condensation
Three human malignancy cell lines were irradiated with 60Co γ-rays. Initial chromatid breaks were measured by using the chemically induced premature chromosome condensation technique. Survival curves of cells exp...
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Chapter
Two-Dimensional Gene Scanning
The large size of many human genes, in combination with the frequent occurrence of many different mutations over the entire gene, severely limits direct diagnosis. Since gene diagnosis by sequencing on a large...