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Open AccessDirect observation and measurement of circumlental space and its relation to anterior chamber angle characteristics in iridotomized phakic eyes with primary angle closure disease
Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma...
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Open AccessTreatment Preferences and Factors Influencing the Management of Primary Angle-Closure Suspect in China: A National Survey Study
This study explored the current views of ophthalmologists in China on the preferred strategy and the primary influencing factors in managing primary angle-closure suspect (PACS).
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Article
Open AccessSecondary ocular hypertension due to tentorial dural arteriovenous fistula: a case report
Tentorial dural arteriovenous fistulas (TDAVFs) are abnormal shunts between meningeal arteries and the intradural venous system located in the tentorial dura mater, which typically manifest with haemorrhage or...
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Article
Low-Complexity Beamspace DOA Estimation for Coherently Distributed Sources in Massive MIMO Systems
Coherently Distributed (CD) sources are suitable for practical direction-of-arrival (DOA) estimation in massive Multiple-Input Multiple-Output (MIMO) communication systems. However, massive MIMO systems employ...
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Article
Open AccessUnilateral pigmented paravenous retinochoroidal atrophy with acute angle-closure glaucoma: a case report
Pigmented paravenous retinochoroidal atrophy (PPRCA) is an uncommon fundus disease characterized by perivenous aggregations of pigment clumps and retinochoroidal atrophy distributed along the retinal veins. We...
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Article
Global desert variation under climatic impact during 1982–2020
Deserts are important landscapes on the earth and their variations have impacts on global climate through feedback processes. However, there is a limited understanding of the climatic controls on the spatial a...
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Article
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a unique component of the ubiquitin–proteasome system (UPS), which has multiple activities in maintaining intracellular ubiquitin levels. We previously repor...
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Article
Open AccessA new dataset for mongolian online handwritten recognition
This paper introduces a new traditional Mongolian word-level online handwriting dataset, MOLHW. The dataset consists of handwritten Mongolian words, including 164,631 samples written by 200 writers and coverin...
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Article
Regional differences in carbon trading prices and their spatially driven mechanisms: evidence from China
With ecological civilization becoming an increasingly high profile topic, terms such as carbon neutrality and carbon markets have entered the research landscape. Carbon prices are the core of carbon markets. A...
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Article
Open AccessNLRP3 associated with chronic kidney disease progression after ischemia/reperfusion-induced acute kidney injury
Nod-like receptor protein 3 (NLRP3), as an inflammatory regulator, has been implicated in acute kidney injury (AKI). Failed recovery after AKI can lead to chronic kidney disease (CKD). However, the role of NLR...
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Article
Open AccessHippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI
Acute kidney injury (AKI) is associated with significant morbidity and its chronic inflammation contributes to subsequent chronic kidney disease (CKD) development. Yes-associated protein (YAP), the major trans...
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Article
Open AccessRecent Advances in Phase-Sensitive Optical Time Domain Reflectometry (Ф-OTDR)
Phase-sensitive optical time domain reflectometry (Ф-OTDR) is an effective way to detect vibrations and acoustic waves with high sensitivity, by interrogating coherent Rayleigh backscattering light in sensing ...
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Article
Effects of sulfur limitation on nitrogen and sulfur uptake and lipid accumulation in Scenedesmus acuminatus
Sulfur limitation is a frequently exploited method for inducing lipid accumulation in microalgae. However, there is little understanding of the underlying mechanism of this process. Hence, a study was conducte...
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Open AccessBone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1
Exosomes are small endogenous membrane vesicles that can mediate cell communication by transferring genetic materials. Based on that, exosomes have always been discussed as a cargo carrier for microRNA (miRNA)...
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Open AccessClinical characteristics of 145 patients with corona virus disease 2019 (COVID-19) in Taizhou, Zhejiang, China
The aim of this study was to investigate the clinical characteristics of Corona Virus Disease 2019 in Taizhou, China.
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Open AccessPulmonary alveolar regeneration in adult COVID-19 patients
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Open AccessKnockdown of lncRNA PVT1 inhibits prostate cancer progression in vitro and in vivo by the suppression of KIF23 through stimulating miR-15a-5p
Prostate cancer (PCa) greatly threatens men’s lives, with high incidence and mortality. Recently, the research of long non-coding RNAs (lncRNAs) has made breakthroughs in the development of human cancers. This...
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Article
Open AccessMetformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation
Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients develo** polycystic kidney disease and leading to a decline of renal function. TSC is caused ...
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Article
Growth, biochemical composition, and photosynthetic performance of Scenedesmus acuminatus during nitrogen starvation and resupply
Many microalgae store energy as triacylglycerols under certain environmental conditions. Nitrogen limitation is recognized as an efficient lipid-accumulation trigger in microalgae. Here, biochemical compositio...
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Article
Open AccessInhibiting 4E-BP1 re-activation represses podocyte cell cycle re-entry and apoptosis induced by adriamycin
Podocyte loss is one of the determining factors for the progression toward glomerulosclerosis. Podocyte is terminally differentiated and does not typically proliferate following injury and loss. However, recen...