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Article
Open AccessCharacteristics of blood immune cell profile and their correlation with disease progression in patients infected with HIV-1
Antiretroviral therapy (ART) can reduce viral load in individuals infected with human immunodeficiency virus (HIV); however, some HIV-infected individuals still cannot achieve optimal immune recovery even afte...
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Article
Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin
Our previous studies found that the H1-50 monoclonal antibody (mAb) of influenza A virus hemagglutinin (HA) cross-reacted with pancreatic tissue and islet β-cells, and further studies showed that H1-50 mAb bin...
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Chapter and Conference Paper
A Sentence Quality Evaluation Framework for Machine Reading Comprehension Incorporating Pre-trained Language Model
Multi-choice Machine Reading Comprehension (MRC) task involves selecting the correct answer from a limited set of options given a passage and a question. MRC tasks have experienced two main peaks: the explosion o...
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Article
Identification and analysis of B cell epitopes of hemagglutinin of H1N1 influenza virus
The frequent variation of influenza virus hemagglutinin (HA) antigen is the main cause of influenza pandemic. Therefore, the study of B cell epitopes of HA is of great significance in the prevention and contro...
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Article
A 300 nW 10 kHz Relaxation Oscillator with 105 ppm/ \(^{\circ }\) C Temperature Coefficient
An on-chip nanopower RC relaxation oscillator is developed in a 180-nm standard CMOS process, consuming 300 nW while running at 10 kHz. Employing a frequency compensation scheme that reduces the frequency drif...
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Article
Monoclonal Antibody Targeting the HA191/199 Region of H1N1 Influenza Virus Mediates the Damage of Neural Cells
Vaccination is the most effective mean of preventing influenza virus infections. However, vaccination-induced adverse reactions of the nervous system, the causes of which are unknown, lead to concerns on the s...
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Article
Expression and DNA Methylation Status of the Imprinted Genes PEG10 and L3MBTL1 in the Umbilical Cord Blood and Placenta of the Offspring of Assisted Reproductive Technology
The aim of this study is to investigate the expression and DNA methylation status of the imprinted genes PEG10 and L3MBTL1 in the offspring of assisted reproductive technology (ART). The ART group consists of ...
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Article
Open AccessTwo kinds of rare light chain cast nephropathy caused by multiple myeloma: case reports and literature review
Light chain cast nephropathy (LCCN) is the most common renal disease caused by multiple myeloma (MM). In addition to ordinary light chain protein casts, there are a few rare casts with unique shapes, including...
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Article
Precise measurement of attenuation length of the JUNO liquid scintillator
The Jiangmen Underground Neutrino Observatory has critical requirements on quality of the liquid scintillator, one of which is long attenuation length.
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Article
Open AccessSMRT sequencing revealed to be an effective method for ADTKD-MUC1 diagnosis through follow-up analysis of a Chinese family
We reported a large Chinese family diagnosed with autosomal dominant tubulointerstitial kidney disease caused by MUC1 mutation (ADTKD-MUC1). Cytosine duplication within a string of 7 cytosines in the variable-num...
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Article
Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China
This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit (ICU) for complications from coronavirus disease 2019 (COVID-19) at the First Affil...
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Article
The faster-onset antidepressant effects of hypidone hydrochloride (YL-0919)
Hypidone hydrochloride (YL-0919), is a novel structural antidepressant candidate as a triple selective serotonin re-uptake inhibitor (SSRI), 5-HT1A partial agonist and 5-HT6 agonist. Here, we investigated the rap...
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Article
Localization Analysis of Heterophilic Antigen Epitopes of H1N1 Influenza Virus Hemagglutinin
Previous studies have indicated that two monoclonal antibodies (mAbs; A1-10 and H1-84) of the hemagglutinin (HA) antigen on the H1N1 influenza virus cross-react with human brain tissue. It has been proposed th...
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Article
A prepared anti-MSTN polyclonal antibody reverses insulin resistance of diet-induced obese rats via regulation of PI3K/Akt/mTOR&FoxO1 signal pathways
Suppression of myostatin (MSTN) is associated with skeletal muscle atrophy and insulin resistance. However, the mechanisms by which MSTN regulates insulin resistance are not well known. We have explored the si...
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Article
Open AccessHuman papillomavirus-related psychosocial impact of patients with genital warts in China: a hospital-based cross-sectional study
Genital warts (GW) are the most common sexually transmitted infections. To date, few studies using a human papillomavirus (HPV)-specific questionnaire have focused on the impact of quality of life (QoL) among ...
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Article
Open AccessImpact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study
Information on the health-related quality of life (HRQoL) of patients with genital warts (GW) in populations in mainland China is still limited. The aim of the study was to use a generic instrument to measure ...
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Article
RETRACTED ARTICLE: Cytotoxic activities of tubeimoside-2 on human hepatoma HepG2 cells by induction of G2/M phase arrest and apoptosis in a p53-dependent manner
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Article
Gene expression profiling of phenylbutyrate induced differentiation of glioma cells by cDNA array
Objective: To analyze the changes of gene expression in phenylbutyrate induced differentiation of glioma cells. Methods: The expression levels of 14000 genes in glioma cells before and after inducement with so...
