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  1. Article

    Open Access

    Unraveling the genetic complexities of combined retinal dystrophy and hearing impairment

    Usher syndrome, the most prevalent cause of combined hereditary vision and hearing impairment, is clinically and genetically heterogeneous. Moreover, several conditions with phenotypes overlap** Usher syndro...

    Paulina Bahena, Narsis Daftarian, Reza Maroofian, Paola Linares in Human Genetics (2022)

  2. Article

    Open Access

    The perception threshold of the panda illusion, a particular form of 2D pulse-width-modulated halftone, correlates with visual acuity

    To call attention to the danger of extinction of the panda bear, the Lithuanian artist Ilja Klemencov created the artwork “They can disappear”. The illustration is composed of black-and-white zigzagged lines, ...

    Torsten Straßer, Anne Kurtenbach, Hana Langrová, Laura Kuehlewein in Scientific Reports (2020)

  3. No Access

    Article

    MACUSTAR: Entwicklung und klinische Validierung von funktionellen, strukturellen und patientenberichteten Endpunkten bei intermediärer altersabhängiger Makuladegeneration

    Für Therapiestudien bei intermediärer altersabhängiger Makuladegeneration (iAMD) gibt es bislang keine validierten klinischen Endpunkte.

    Jan H. Terheyden, Robert P. Finger, Steffen Schmitz-Valckenberg in Der Ophthalmologe (2019)

  4. No Access

    Article

    Phenotypic spectrum of autosomal recessive retinitis pigmentosa without posterior column ataxia caused by mutations in the FLVCR1 gene

    Posterior column ataxia and retinitis pigmentosa (PCARP) is a rare form of syndromic RP associated with mutations in the FLVCR1 gene. Recent evidence has suggested a spectrum in the phenotype depending on the gen...

    Laura Kuehlewein, Ludger Schöls in Graefe's Archive for Clinical and Experime… (2019)

  5. Article

    Open Access

    Intravitreal Ranibizumab Therapy for Diabetic Macular Edema in Routine Practice: Two-Year Real-Life Data from a Non-interventional, Multicenter Study in Germany

    The prospective, non-interventional OCEAN study examined the use of intravitreal ranibizumab injections for the treatment of diabetic macular oedema (DME) in a real-world setting in Germany.

    Focke Ziemssen, Joachim Wachtlin, Laura Kuehlewein in Diabetes Therapy (2018)