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Article
Open AccessT-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate
Most effector CD8+ T cells die, while some persist and become either “effector” (TEM) or “central” (TCM) memory T cells. Paradoxically, effector CD8+ T cells with greater memory potential have higher levels of th...
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Article
A B-1a cell subset induces Foxp3− T cells with regulatory activity through an IL-10-independent pathway
Regulatory T (Treg) cells play a critical role in the maintenance of tolerance. B-1a cells belong to a specific and functionally important B-cell subset that exerts its regulatory role through the production o...