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Article

T-cell receptor signal strength and epigenetic control of Bim predict memory CD8⁺ T-cell fate

Most effector CD8⁺ T cells die, while some persist and become either “effector” (T_EM) or “central” (T_CM) memory T cells. Paradoxically, effector CD8⁺ T cells with greater memory potential have higher levels of th...

Kun-Po Li, Brian H. Ladle, Sema Kurtulus, Allyson Sholl… in Cell Death & Differentiation (2020)