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Open AccessAssociation of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study
The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed ...
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Article
Open AccessDietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study
Inflammatory, insulin and oestrogenic pathways have been linked to breast cancer (BC). We aimed to examine the relationship between pre-diagnostic dietary patterns related to these mechanisms and BC survival.
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Article
Open AccessPan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition
Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metaboli...
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Article
Open AccessCirculating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort
Inflammation has been hypothesized to play a role in the development and progression of breast cancer and might differently impact breast cancer risk among pre and postmenopausal women. We performed a nested c...
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Open AccessLifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort
Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we obs...
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Article
Open AccessDietary intake of trans fatty acids and breast cancer risk in 9 European countries
Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone recepto...
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Article
Open AccessCoffee consumption and overall and cause-specific mortality: the Norwegian Women and Cancer Study (NOWAC)
Coffee consumption has previously been reported to reduce overall and cause-specific mortality. We aimed to further investigate this association by coffee brewing methods and in a population with heavy coffee ...
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Article
Open AccessPhysical activity and blood gene expression profiles: the Norwegian Women and Cancer (NOWAC) Post-genome cohort
The influence of physical activity (PA) on the immune system has emerged as a new field of research. Regular PA may promote an anti-inflammatory state in the body, thus contributing to the down-regulation of p...
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Open AccessNutrient-wide association study of 92 foods and nutrients and breast cancer risk
Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association...
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Article
Open AccessTranscription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer
Lung cancer is the leading cause of cancer deaths. Novel predictive biomarkers are needed to improve treatment selection and more accurate prognostication. PAX6 is a transcription factor with a proposed tumour...
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Open AccessExcerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway
The goal of biomarker research is to identify clinically valid markers. Despite decades of research there has been disappointingly few molecules or techniques that are in use today. The “1st International NTNU...
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Open AccessWhole-Blood Gene Expression Profiles in Large-Scale Epidemiological Studies: What Do They Tell?
In nutrigenomics, gene expression profiling is used to investigate transcriptional mechanisms associated with nutrients and diet. Blood samples collected in the framework of dietary interventions and epidemiol...
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Open AccessFish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort
Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumpti...