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  1. No Access

    Article

    Can breast MRI and adjunctive Doppler ultrasound improve the accuracy of predicting pathological complete response after neoadjuvant chemotherapy?

    To examine the accuracy of MRI and Doppler ultrasound (US) for detecting residual tumor after neoadjuvant chemotherapy (NAC) for breast cancer and evaluate whether adjunctive Doppler US improves the MRI accuracy.

    Kazuaki Nakashima, Takayoshi Uematsu, Taiyo L. Harada, Kaoru Takahashi in Breast Cancer (2021)

  2. No Access

    Article

    Randomized study of prevention of gastrointestinal toxicities by nutritional support using an amino acid-rich elemental diet during chemotherapy in patients with esophageal cancer (KDOG 1101)

    This randomized study was designed to evaluate the clinical effect of an elemental diet during chemotherapy in patients with esophageal cancer.

    Chikatoshi Katada, Saeko Fukazawa, Mitsuhiro Sugawara, Yasutoshi Sakamoto in Esophagus (2021)

  3. Article

    Open Access

    Self-weighing frequency and the incidence of type 2 diabetes: post hoc analysis of a cluster-randomized controlled trial

    Frequent self-weighing is associated with weight loss and maintenance, but the relationship between frequent self-weighing and the incidence of type 2 diabetes (T2D) remains unclear. The study aim was to exami...

    Naoki Sakane, Yoshitake Oshima, Kazuhiko Kotani, Akiko Suganuma in BMC Research Notes (2020)

  4. No Access

    Article

    Is the presence of edema and necrosis on T2WI pretreatment breast MRI the key to predict pCR of triple negative breast cancer?

    Given that a pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is an important prognostic factor, evaluating pretreatment imaging findings is important. Outcomes for triple negative bre...

    Taiyo L. Harada, Takayoshi Uematsu, Kazuaki Nakashima, Takashi Sugino in European Radiology (2020)

  5. No Access

    Article

    MRI-detected breast lesions: clinical implications and evaluation based on MRI/ultrasonography fusion technology

    Magnetic resonance imaging (MRI) is a highly sensitive imaging modality that frequently reveals additional breast lesions that are occult on mammography and ultrasonography (US) and are thus difficult to diagn...

    Kazuaki Nakashima, Takayoshi Uematsu, Taiyo L. Harada in Japanese Journal of Radiology (2019)

  6. No Access

    Article

    Does breast cancer growth rate really depend on tumor subtype? Measurement of tumor doubling time using serial ultrasonography between diagnosis and surgery

    Breast cancer growth is generally expected to differ between tumor subtypes. We aimed to evaluate tumor doubling time (DT) using ultrasonography and verify whether each tumor subtype has a unique DT.

    Kazuaki Nakashima, Takayoshi Uematsu, Kaoru Takahashi in Breast Cancer (2019)

  7. No Access

    Article

    Comparison of visibility of circumscribed masses on Digital Breast Tomosynthesis (DBT) and 2D mammography: are circumscribed masses better visualized and assured of being benign on DBT?

    To compare the visibility of circumscribed masses on digital breast tomosynthesis (DBT) images and 2D mammograms and determine the usefulness of DBT for differentiation between benign and malignant circumscrib...

    Kazuaki Nakashima, Takayoshi Uematsu, Takahiro Itoh, Kaoru Takahashi in European Radiology (2017)

  8. No Access

    Article

    Real-time virtual sonography examination and biopsy for suspicious breast lesions identified on MRI alone

    The purpose of our study was to assess whether there is a potential additional value of real-time virtual sonography (RVS) to second-look ultrasound (US) examination and biopsy for breast lesions identified on...

    Takayoshi Uematsu, Kaoru Takahashi, Seiichiro Nishimura in European Radiology (2016)

  9. No Access

    Article

    Association between pharmacokinetic variables and neutropenia after treatment with docetaxel, cisplatin, and 5-fluorouracil in patients with esophageal squamous cell carcinoma

    Combined chemotherapy with cisplatin, 5-fluorouracil, and docetaxel (DCF) is a promising regimen for the treatment of esophageal squamous cell carcinoma (ESCC). However, careful attention must be paid to sever...

    Mitsuhiro Sugawara, Chikatoshi Katada, Toshiaki Komatsu, Kaoru Takahashi in Esophagus (2015)

  10. No Access

    Article

    Metastatic breast carcinoma of the abdominal wall muscle: a case report

    Metastasis from breast carcinoma is an uncommon occurrence in skeletal muscle, compared to local invasion into muscle from direct tumor spread. A 49-year-old woman was referred to our hospital with an 8.5-cm m...

    Akiko Ogiya, Kaoru Takahashi, Mutsumi Sato, Yoshiko Kubo, Noriko Nishikawa in Breast Cancer (2015)

  11. Article

    Open Access

    Efficacy of a 3-month lifestyle intervention program using a Japanese-style healthy plate on body weight in overweight and obese diabetic Japanese subjects: a randomized controlled trial

    The portion size of food is a determinant of energy intake, linking with obese traits. A healthy plate for portion control has recently been made in a Japanese style. The aim of the current study was to assess...

    Keiko Yamauchi, Tomomi Katayama, Takahiro Yamauchi, Kazuhiko Kotani in Nutrition Journal (2014)

  12. No Access

    Article

    IgG4-related sclerosing disease of the breast successfully treated by steroid therapy

    IgG4-related sclerosing disease was first identified and defined in the twenty-first century. In this pathology, the serum IgG4 level increases and IgG4-positive plasma cells and lymphocytes infiltrate organs ...

    Akiko Ogiya, Kumiko Tanaka, Yukiko Tadokoro, Mariko Kikutani in Breast Cancer (2014)

  13. No Access

    Article

    Retrospective evaluation of adverse events of neoadjuvant or induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in esophageal squamous cell carcinoma

    Neoadjuvant or induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF) is regarded as one of the most promising regimens for locally advanced esophageal squamous cell carcinoma (ESCC), but h...

    Mitsuhiro Sugawara, Chikatoshi Katada, Natsuya Katada, Kaoru Takahashi in Esophagus (2013)

  14. Article

    Open Access

    Japan Diabetes Outcome Intervention Trial-1(J-DOIT1), a nationwide cluster randomized trial of type 2 diabetes prevention by telephone-delivered lifestyle support for high-risk subjects detected at health checkups: rationale, design, and recruitment

    Lifestyle modifications are considered the most effective means of delaying or preventing the development of type 2 diabetes (T2DM). To contain the growing population of T2DM, it is critical to clarify effecti...

    Naoki Sakane, Kazuhiko Kotani, Kaoru Takahashi, Yoshiko Sano in BMC Public Health (2013)

  15. No Access

    Article

    Clip placement after an 11-gauge vacuum-assisted stereotactic breast biopsy: correlation between breast thickness and clip movement

    To retrospectively evaluate the accuracy of clip placement on the basis of measurements obtained on pre- and post-vacuum-assisted 11-gauge stereotactic biopsy mammograms and to analyze the factors that can pre...

    Takayoshi Uematsu, Masako Kasami, Kaoru Takahashi, Junichiro Watanabe in Breast Cancer (2012)

  16. No Access

    Article

    Is lymphovascular invasion degree one of the important factors to predict neoadjuvant chemotherapy efficacy in breast cancer?

    Patients who achieve pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) have favorable disease-free survival rates. A few studies have suggested that lymphovascular invasion degree may pla...

    Takayoshi Uematsu, Masako Kasami, Junichiro Watanabe, Kaoru Takahashi in Breast Cancer (2011)

  17. Article

    Open Access

    The association of the Clock 3111 T/C SNP with lipids and lipoproteins including small dense low-density lipoprotein: results from the Mima study

    The clock molecule plays major roles in circadian rhythmicity and regulating lipid and glucose metabolism in peripheral organs. Disruption of the circadian rhythm can lead to cardiometabolic disorders. The exi...

    Kokoro Tsuzaki, Kazuhiko Kotani, Yoshiko Sano, Shinji Fujiwara in BMC Medical Genetics (2010)

  18. No Access

    Article

    Early prediction of a long-term outcome by neutrophil-FISH in patients with CML receiving imatinib mesylate

    Naoto Takahashi, Yoshihiro Kameoka, Hiroyuki Tagawa in International Journal of Hematology (2010)

  19. No Access

    Chapter

    FOXP Genes, Neural Development, Speech and Language Disorders

    Foxp subfamily genes were recently recognized to be members of the Fox gene family. Foxp subfamily members contain a zinc finger domain and a leucine zipper motif in addition to a forkhead domain...

    Hiroshi Takahashi, Kaoru Takahashi, Fu-Chin Liu in Forkhead Transcription Factors (2010)

  20. No Access

    Article

    Diagnostic mammography and ultrasonography for palpable and nonpalpable breast cancer in women aged 30 to 39 years

    Purpose: To investigate the relationship between the tumor size of breast cancer by palpation and the sensitivity of mammography (MMG) and ultrasonography (US), and which modality can detect nonpalpable breast...

    Tomo Osako, Takuji Iwase, Kaoru Takahashi, Kotaro lijima, Yumi Miyagi in Breast Cancer (2007)

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