SpringerLink
Log in

Metastatic breast carcinoma of the abdominal wall muscle: a case report

  • Case Report
  • Published:
Breast Cancer Aims and scope Submit manuscript

Abstract

Metastasis from breast carcinoma is an uncommon occurrence in skeletal muscle, compared to local invasion into muscle from direct tumor spread. A 49-year-old woman was referred to our hospital with an 8.5-cm mass in the right breast. Core needle biopsy revealed metaplastic carcinoma with squamous metaplasia. The mass was rapidly growing and metaplastic, so mastectomy with dissection of axillary lymph nodes was performed. Pathological examination showed metaplastic carcinoma, histological grade 3, triple negative, and a MIB-1 labeling index of 80%. Six months postoperatively, during adjuvant chemotherapy treatment, she reported numbness and pain in the right lateral thigh and a mass in the right lower abdomen. Computed tomography revealed multiple lined masses in the abdominal wall and iliac muscle. Core needle biopsy showed metastatic breast carcinoma. Radio- and chemotherapy were administered, but the mass in the muscle became enlarged. To control her pain, a combined treatment with morphine, fentanyl, ketamine, antiepilepsy drug, and NSAIDs was administered. Liver metastasis appeared 9 months (15 months postoperatively) after recognition of muscle metastasis, and the patient died 16 months postoperatively. Skeletal muscle metastasis is uncommon, and therapeutic intervention is mainly palliative. The most common symptom of skeletal muscle metastasis is pain; thus, pain control is a pivotal goal of treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Germany)

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Spitzer SG, Bersani TA, Mejico LJ. Multiple bilateral extraocular muscle metastases as the initial manifestation of breast cancer. J Neuroophthalmol. 2005;25:37–9.

    Article  PubMed  Google Scholar 

  2. Shiina T, Minoshima S, Uno K, Arimizu N, Kitakata Y. Uptake of technetium-99m MDP by skeletal muscles in breast Paget’s disease. Jpn J Clin Radiol. 1992;37:1169–71 (in Japanese with English abstract).

    Google Scholar 

  3. Doshi R, Fowler T. Proximal myopathy due to discrete carcinomatous metastases in muscle. J Neurol Neurosurg Psychiatry. 1983;46:358–60.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  4. Yoshy C, Montana M. CT findings of metastatic breast carcinoma involving muscle. J Comput Assist Tomogr. 1985;9:967–8.

    Article  CAS  PubMed  Google Scholar 

  5. Eiber AM, Wiener SN. “Photopenic” bone lesion secondary to erector spinae muscle infiltration by breast carcinoma. Clin Nucl Med. 1986;11:194–5.

    Article  CAS  PubMed  Google Scholar 

  6. Hazeltine M, Duranceau L, Gariepy G. Presentation of breast carcinoma as Volkmann’s contracture due to skeletal muscle metastases. J Rheumatol. 1990;17:1097–9.

    CAS  PubMed  Google Scholar 

  7. Tosios K, Vasilas A, Arsenopoulos A. Metastatic breast carcinoma of the masseter: case report. J Oral Maxillofac Surg. 1992;50:304–6.

    Article  CAS  PubMed  Google Scholar 

  8. Sahai S, Leigh D. Metastasis of adenocarcinoma of breast to gluteus medius. Iowa Med. 1995;85:369–70.

    CAS  PubMed  Google Scholar 

  9. Ahuja AT, King AD, Bradley MJ, Yeo WW, Mok TS, Metreweli C. Sonographic findings in masseter-muscle metastases. J Clin Ultrasound. 2000;28:299–302.

    Article  CAS  PubMed  Google Scholar 

  10. Tanaka K, Ishida T, Shirono J, Ajiki T, Nakazawa K, Okumura S, et al. A case of inflammatory breast carcinoma with psoas muscle metastasis. J Jpn Surg Assoc. 1998;59:89–94 (in Japanese with English abstract).

    Google Scholar 

  11. Liu Y, Ghesani N, Mirani N, Zuckier LS. PET–CT demonstration of extensive muscle metastases from breast cancer. Clin Nucl Med. 2006;31:266–8.

    Article  CAS  PubMed  Google Scholar 

  12. Peckham EL, Giblen G, Kim AK, Sirdofsky MD. Bilateral extraocular muscle metastasis from primary breast cancer. Neurology. 2005;65:74.

    Article  CAS  PubMed  Google Scholar 

  13. Oh K, Imamura M, Murase K, Saitou M, Ito T, Hirota S, et al. A case of recurrent breast carcinoma demonstrating multiple skeletal muscle metastases. Jpn J Breast Cancer. 2009;24:753–7.

    Google Scholar 

  14. Tuoheti Y, Okada K, Osanai T, Nishida J, Ehara S, Hashimoto M, et al. Skeletal muscle metastases of carcinoma: a clinicopathological study of 12 cases. Jpn J Clin Oncol. 2004;34:210–4.

    Article  PubMed  Google Scholar 

  15. Plaza JA, Perez-Montiel D, Mayerson J, Morrison C, Suster S. Metastases to soft tissue: a review of 118 cases over a 30-year period. Cancer. 2008;112:193–203.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Breast Surgery, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan

    Akiko Ogiya, Kaoru Takahashi, Mutsumi Sato, Yoshiko Kubo, Noriko Nishikawa, Mariko Kikutani, Yukiko Tadokoro & Kumiko Tanaka

  2. Department of Breast Imaging and Breast Intervention, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan

    Takayoshi Uematsu

  3. Department of Medical Oncology, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan

    Junichiro Watanabe

  4. Department of Pathology, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan

    Masako Kasami

  5. Department of Multidisciplinary Therapy for Breast Cancer, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan

    Seiji Yamasaki

Authors
  1. Akiko Ogiya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kaoru Takahashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mutsumi Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yoshiko Kubo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Noriko Nishikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mariko Kikutani
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yukiko Tadokoro
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Kumiko Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Takayoshi Uematsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Junichiro Watanabe
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Masako Kasami
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Seiji Yamasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Akiko Ogiya.

About this article

Cite this article

Ogiya, A., Takahashi, K., Sato, M. et al. Metastatic breast carcinoma of the abdominal wall muscle: a case report. Breast Cancer 22, 206–209 (2015). https://doi.org/10.1007/s12282-012-0352-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12282-012-0352-3

Keywords

Search

Navigation