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  1. Article

    Open Access

    Extracellular vesicle-mediated transfer of miRNA-1 from primary tumors represses the growth of distant metastases

    Metastases originate from primary tumors and reach distant organs. Growing evidence suggests that metastases are under the control of primary tumors even outside the primary site; however, the mechanisms by wh...

    Chae-Yi Kim, Kang-Hoon Lee, Keun Hong Son in Experimental & Molecular Medicine (2024)

  2. No Access

    Chapter and Conference Paper

    Principal Component Analysis over the Boolean Circuit Within TFHE Scheme

    In today’s information-driven world, the need to protect personal data while maintaining efficient data processing capabilities is crucial. Homomorphic Encryption (HE) has emerged as a potential solution, allo...

    Hyun Jung Doh, Joon Soo Yoo, Mi Yeon Hong in Information Security Applications (2024)

  3. No Access

    Chapter and Conference Paper

    Cheap and Fast Iterative Matrix Inverse in Encrypted Domain

    Homomorphic encryption (HE) is a promising technique for preserving the privacy of sensitive data by enabling computations to be performed on encrypted data. However, due to the limitations of arithmetic HE sc...

    Tae Min Ahn, Kang Hoon Lee, Joon Soo Yoo, Ji Won Yoon in Computer Security – ESORICS 2023 (2024)

  4. No Access

    Article

    Extensive giant fusiform aneurysm in Sneddon syndrome

    Han Uk Ryu, Kang Hoon Lee, Seong Yoon Cho, Hyun Goo Kang in Neurological Sciences (2023)

  5. Article

    Open Access

    The landscape of PBMC methylome in canine mammary tumors reveals the epigenetic regulation of immune marker genes and its potential application in predicting tumor malignancy

    Genome-wide dysregulation of CpG methylation accompanies tumor progression and characteristic states of cancer cells, prompting a rationale for biomarker development. Understanding how the archetypic epigeneti...

    A-Reum Nam, Min Heo, Kang-Hoon Lee, Ji-Yoon Kim, Sung-Ho Won, Je-Yoel Cho in BMC Genomics (2023)

  6. No Access

    Chapter and Conference Paper

    Discretization Error Reduction for High Precision Torus Fully Homomorphic Encryption

    In recent history of fully homomorphic encryption, bootstrap** has been actively studied throughout many HE schemes. As bootstrap** is an essential process to transform somewhat homomorphic encryption sche...

    Kang Hoon Lee, Ji Won Yoon in Public-Key Cryptography – PKC 2023 (2023)

  7. Article

    Retraction Note: Development and application of a digital curation system to promote total creative personality based on multimedia

    Jeong-** Youn, Su-Jeong Jeong, Kang-Hoon Lee in Multimedia Tools and Applications (2022)

  8. No Access

    Article

    RETRACTED ARTICLE: Development and application of a digital curation system to promote total creative personality based on multimedia

    This study aims to develop a teaching and learning model and curation system based on multimedia. This curation system is a model for fostering convergent human resources with creative solutions based on compr...

    Jeong-** Youn, Su-Jeong Jeong, Kang-Hoon Lee in Multimedia Tools and Applications (2021)

  9. No Access

    Chapter and Conference Paper

    Efficient Adaptation of TFHE for High End-to-End Throughput

    Homomorphic Encryption (HE) allows to process over user’s encrypted data. There are various HE schemes including TFHE, which offers homomorphic binary gate operation combined with bootstrap**. In most used c...

    Kang Hoon Lee, Ji Won Yoon in Information Security Applications (2021)

  10. Article

    Open Access

    Alternative methylation of intron motifs is associated with cancer-related gene expression in both canine mammary tumor and human breast cancer

    Canine mammary tumor (CMT) has long been considered as a good animal model for human breast cancer (HBC) due to their pathological and biological similarities. However, only a few aspects of the epigenome have...

    A-Reum Nam, Kang-Hoon Lee, Hyeon-Ji Hwang, Johannes J. Schabort in Clinical Epigenetics (2020)

  11. Article

    Open Access

    Author Correction: Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Kang-Hoon Lee, Tae-** Shin, Wan-Hee Kim, Je-Yoel Cho in Scientific Reports (2019)

  12. No Access

    Article

    Transposable element-mediated structural variation analysis in dog breeds using whole-genome sequencing

    Naturally occurring diseases in dogs provide an important animal model for studying human disease including cancer, heart disease, and autoimmune disorders. Transposable elements (TEs) make up ~ 31% of the dog (C...

    Songmi Kim, Seyoung Mun, Taemook Kim, Kang-Hoon Lee, Keunsoo Kang in Mammalian Genome (2019)

  13. Article

    Open Access

    Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors

    Breast cancer (BC) is one of the most common cancers in both women and female dogs. Methylation changes of LINE-1 have been reported in human cancers. The aim of this study was to determine the hypomethylation...

    Kang-Hoon Lee, Tae-** Shin, Wan-Hee Kim, Je-Yoel Cho in Scientific Reports (2019)

  14. Article

    Open Access

    The Role of Nitrosamine (NNK) in Breast Cancer Carcinogenesis

    Smoking cigarettes is one of the most concerning issues that leads to tobacco-related cancers and can even result in death. Therefore, these issues should be addressed with a great sense of urgency with low-co...

    Nomundelger Gankhuyag, Kang-Hoon Lee in Journal of Mammary Gland Biology and Neopl… (2017)

  15. Article

    Open Access

    Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication

    The eradication rate of Helicobacter pylori (H. pylori) with triple therapy which was considered as standard first-line treatment has decreased to 70–85%. The aim of this study is to compare 7-day triple therapy ...

    Ji Young Chang, Ki-Nam Shim, Chung Hyun Tae, Ko Eun Lee, Jihyun Lee in BMC Gastroenterology (2017)

  16. No Access

    Article

    Large interrelated clusters of repetitive elements (REs) and RE arrays predominantly represent reference mouse chromosome Y

    The vast majority of the mouse and human genomes consist of repetitive elements (REs), while protein-coding sequences occupy only ∼3 %. It has been reported that the Y chromosomes of both species are highly po...

    Kang-Hoon Lee, Woo-Chan Kim, Kyung-Seop Shin, Jeong-Kyu Roh in Chromosome Research (2013)

  17. Article

    Open Access

    Injury-elicited stressors alter endogenous retrovirus expression in lymphocytes depending on cell type and source lymphoid organ

    Murine leukemia virus-type endogenous retroviruses (MuLV-ERVs) constitute ~10% of the mouse genome and are associated with various pathophysiologic processes. In this study, we examined whether MuLV-ERVs’ resp...

    Kang-Hoon Lee, Debora Lim, Tajia Green, David Greenhalgh, Kiho Cho in BMC Immunology (2013)

  18. No Access

    Article

    Identification of a group of Mus dunni endogenous virus-like endogenous retroviruses from the C57BL/6J mouse genome: proviral genomes, strain distribution, expression characteristics, and genomic integration profile

    About 10 % of the mouse genome is occupied by sequences associated with endogenous retroviruses (ERVs). However, a comprehensive profile of the mouse ERVs and related elements has not been established yet. In ...

    Kang-Hoon Lee, Ri-Na You, David G. Greenhalgh, Kiho Cho in Chromosome Research (2012)

  19. Article

    Open Access

    Reply to Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice

    This correspondence was written in response to the comments by Young et al. Following careful evaluation of the relevant dataset, each of the points brought up by Young et al. has been addressed in this response....

    Kang-Hoon Lee, Kiho Cho in Retrovirology (2012)

  20. Article

    Open Access

    Cerebellum-specific and age-dependent expression of an endogenous retrovirus with intact coding potential

    Endogenous retroviruses (ERVs), including murine leukemia virus (MuLV) type-ERVs (MuLV-ERVs), are presumed to occupy ~10% of the mouse genome. In this study, following the identification of a full-length MuLV-...

    Kang-Hoon Lee, Makoto Horiuchi, Takayuki Itoh, David G Greenhalgh in Retrovirology (2011)

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