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Article
Open AccessExtracellular vesicle-mediated transfer of miRNA-1 from primary tumors represses the growth of distant metastases
Metastases originate from primary tumors and reach distant organs. Growing evidence suggests that metastases are under the control of primary tumors even outside the primary site; however, the mechanisms by wh...
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Chapter and Conference Paper
Principal Component Analysis over the Boolean Circuit Within TFHE Scheme
In today’s information-driven world, the need to protect personal data while maintaining efficient data processing capabilities is crucial. Homomorphic Encryption (HE) has emerged as a potential solution, allo...
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Chapter and Conference Paper
Cheap and Fast Iterative Matrix Inverse in Encrypted Domain
Homomorphic encryption (HE) is a promising technique for preserving the privacy of sensitive data by enabling computations to be performed on encrypted data. However, due to the limitations of arithmetic HE sc...
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Article
Extensive giant fusiform aneurysm in Sneddon syndrome
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Article
Open AccessThe landscape of PBMC methylome in canine mammary tumors reveals the epigenetic regulation of immune marker genes and its potential application in predicting tumor malignancy
Genome-wide dysregulation of CpG methylation accompanies tumor progression and characteristic states of cancer cells, prompting a rationale for biomarker development. Understanding how the archetypic epigeneti...
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Chapter and Conference Paper
Discretization Error Reduction for High Precision Torus Fully Homomorphic Encryption
In recent history of fully homomorphic encryption, bootstrap** has been actively studied throughout many HE schemes. As bootstrap** is an essential process to transform somewhat homomorphic encryption sche...
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Article
Retraction Note: Development and application of a digital curation system to promote total creative personality based on multimedia
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Article
RETRACTED ARTICLE: Development and application of a digital curation system to promote total creative personality based on multimedia
This study aims to develop a teaching and learning model and curation system based on multimedia. This curation system is a model for fostering convergent human resources with creative solutions based on compr...
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Chapter and Conference Paper
Efficient Adaptation of TFHE for High End-to-End Throughput
Homomorphic Encryption (HE) allows to process over user’s encrypted data. There are various HE schemes including TFHE, which offers homomorphic binary gate operation combined with bootstrap**. In most used c...
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Article
Open AccessAlternative methylation of intron motifs is associated with cancer-related gene expression in both canine mammary tumor and human breast cancer
Canine mammary tumor (CMT) has long been considered as a good animal model for human breast cancer (HBC) due to their pathological and biological similarities. However, only a few aspects of the epigenome have...
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Article
Open AccessAuthor Correction: Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Transposable element-mediated structural variation analysis in dog breeds using whole-genome sequencing
Naturally occurring diseases in dogs provide an important animal model for studying human disease including cancer, heart disease, and autoimmune disorders. Transposable elements (TEs) make up ~ 31% of the dog (C...
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Article
Open AccessMethylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors
Breast cancer (BC) is one of the most common cancers in both women and female dogs. Methylation changes of LINE-1 have been reported in human cancers. The aim of this study was to determine the hypomethylation...
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Article
Open AccessThe Role of Nitrosamine (NNK) in Breast Cancer Carcinogenesis
Smoking cigarettes is one of the most concerning issues that leads to tobacco-related cancers and can even result in death. Therefore, these issues should be addressed with a great sense of urgency with low-co...
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Article
Open AccessTriple therapy versus sequential therapy for the first-line Helicobacter pylori eradication
The eradication rate of Helicobacter pylori (H. pylori) with triple therapy which was considered as standard first-line treatment has decreased to 70–85%. The aim of this study is to compare 7-day triple therapy ...
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Article
Large interrelated clusters of repetitive elements (REs) and RE arrays predominantly represent reference mouse chromosome Y
The vast majority of the mouse and human genomes consist of repetitive elements (REs), while protein-coding sequences occupy only ∼3 %. It has been reported that the Y chromosomes of both species are highly po...
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Article
Open AccessInjury-elicited stressors alter endogenous retrovirus expression in lymphocytes depending on cell type and source lymphoid organ
Murine leukemia virus-type endogenous retroviruses (MuLV-ERVs) constitute ~10% of the mouse genome and are associated with various pathophysiologic processes. In this study, we examined whether MuLV-ERVs’ resp...
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Article
Identification of a group of Mus dunni endogenous virus-like endogenous retroviruses from the C57BL/6J mouse genome: proviral genomes, strain distribution, expression characteristics, and genomic integration profile
About 10 % of the mouse genome is occupied by sequences associated with endogenous retroviruses (ERVs). However, a comprehensive profile of the mouse ERVs and related elements has not been established yet. In ...
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Article
Open AccessReply to Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice
This correspondence was written in response to the comments by Young et al. Following careful evaluation of the relevant dataset, each of the points brought up by Young et al. has been addressed in this response....
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Article
Open AccessCerebellum-specific and age-dependent expression of an endogenous retrovirus with intact coding potential
Endogenous retroviruses (ERVs), including murine leukemia virus (MuLV) type-ERVs (MuLV-ERVs), are presumed to occupy ~10% of the mouse genome. In this study, following the identification of a full-length MuLV-...