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Article
Impact of tetravalent dengue vaccination with screening, ADE, and altered infectivity on single-serotype dengue and Zika transmission
Acquired immunity to a dengue virus serotype (whether by infection or the only licensed dengue vaccine) can produce antibody-dependent enhancement (ADE) in later infections with another dengue serotype, result...
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Article
Open AccessEvaluation of a mosquito home system for controlling Aedes aegypti
Dengue is a significant public health issue that is caused by Aedes spp. mosquitoes. The current vector control methods are unable to effectively reduce Aedes populations and thus fail to decrease dengue transmis...
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Article
Open AccessNovel application of an automated-machine learning development tool for predicting burn sepsis: proof of concept
Sepsis is the primary cause of burn-related mortality and morbidity. Traditional indicators of sepsis exhibit poor performance when used in this unique population due to their underlying hypermetabolic and inf...
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Article
Open AccessThe Optimal Age of Vaccination Against Dengue with an Age-Dependent Biting Rate with Application to Brazil
In this paper we introduce a single serotype transmission model, including an age-dependent mosquito biting rate, to find the optimal vaccination age against dengue in Brazil with Dengvaxia. The optimal vaccin...
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Article
Open AccessEstimating the prevalence of infectious diseases from under-reported age-dependent compulsorily notification databases
National or local laws, norms or regulations (sometimes and in some countries) require medical providers to report notifiable diseases to public health authorities. Reporting, however, is almost always incompl...
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Article
Open AccessModelling the impact of the long-term use of insecticide-treated bed nets on Anopheles mosquito biting time
Evidence of changing in biting and resting behaviour of the main malaria vectors has been mounting up in recent years as a result of selective pressure by the widespread and long-term use of insecticide-treate...
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Article
Open AccessThe risk of dengue for non-immune foreign visitors to the 2016 summer olympic games in Rio de Janeiro, Brazil
Rio de Janeiro in Brazil will host the Summer Olympic Games in 2016. About 400,000 non-immune foreign tourists are expected to attend the games. As Brazil is the country with the highest number of dengue cases...
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Article
Parameter estimation for the stochastic SIS epidemic model
In this paper we estimate the parameters in the stochastic SIS epidemic model by using pseudo-maximum likelihood estimation (pseudo-MLE) and least squares estimation. We obtain the point estimators and ...
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Article
Open AccessInjury-elicited stressors alter endogenous retrovirus expression in lymphocytes depending on cell type and source lymphoid organ
Murine leukemia virus-type endogenous retroviruses (MuLV-ERVs) constitute ~10% of the mouse genome and are associated with various pathophysiologic processes. In this study, we examined whether MuLV-ERVs’ resp...
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Article
Open AccessAn assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns
To apply the modified pediatric RIFLE criteria for severity of acute kidney injury (AKI) to pediatric burn ICU patients and to evaluate the overall incidence of AKI, risk factors for AKI and influence of AKI o...
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Article
Backward bifurcation, equilibrium and stability phenomena in a three-stage extended BRSV epidemic model
In this paper we consider the phenomenon of backward bifurcation in epidemic modelling illustrated by an extended model for Bovine Respiratory Syncytial Virus (BRSV) amongst cattle. In its simplest form, backw...
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Article
Identification of putative endogenous retroviruses actively transcribed in the brain
Remnant proviral sequences in the genome resulting from the ancient germline infection of exogenous retroviruses are called endogenous retroviruses (ERVs). The transcriptional activation of human ERVs (HERVs) ...
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Article
Open AccessGenome-wide changes in expression profile of murine endogenous retroviruses (MuERVs) in distant organs after burn injury
Previous studies have shown that burn-elicited stress signals alter expression of certain murine endogenous retroviruses (MuERVs) in distant organs of mice. These findings suggest that MuERVs may participate i...
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Article
Optimal Filters with Multiresolution Apertures
This paper presents an extension to the recently introduced class of nonlinear filters known as Aperture Filters. By taking a multiresolution approach, it can be shown that more accurate filtering results (in ter...
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Article
The general mixing of addicts and needles in a variable-infectivity needle-sharing environment
In this paper we develop and analyse a model for the spread of HIV/AIDS amongst a population of injecting drug users. The model we discuss focuses on the transmission of HIV through the sharing of contaminate...
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Article
Book review
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Article
Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation
Nonmelanoma skin cancers (NMSC) are among the most common malignancies in the world. Typically, these neoplasms grow slowly and are comparatively indolent in their clinical behavior. The most frequent molecula...
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Article
Vaccination in density-dependent epidemic models
This paper examines the effect of vaccination for an epidemic model where the death rate depends on the number of individuals in the population. The basic model which is described is based on measles or other ...
