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Low dose alpha 2 antagonist action on rat opioid analgesia and tolerance
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Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgery
In previous animal studies, a prior exposure to nonsteroidal anti-inflammatory drugs (NSAID) augmented opioid drug potency. This study was designed to answer the question whether a similar effect can be attain...
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Cognitive effects of neurotoxic lesions of the nucleus basalis magnocellularis in rats: Differential roles for corticopetal versus amygdalopetal projections
The cholinergic hypothesis states that cholinergic neurons of the basal forebrain nucleus basalis magnocellularis (nbm) that project to cortical and amy-gdalar targets play an important role in memory. Biochem...
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Morphine decreasesin vivo catechol activity in the rostral ventrolateral medulla
Decreased neck extension assessed at the bedside is a predictor of unanticipated difficult intubation. Neck extensions of < 5 cm, in conjunction with the Mallampati airway classification, should become a routi...
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Abstract
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Article
Effects of Morphine and its Antagonists on Release of Cerebral Cortical Acetylcholine
SEVERAL, studies have shown that the narcotic analgesic morphine and morphine-like compounds reduce the release of acetylcholine (ACh) at peripheral cholinergic junctions1–3, but there is relatively little eviden...
