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Article
Open Accesse-Consent in UK academic-led clinical trials: current practice, challenges and the need for more evidence
During the COVID-19 pandemic, in-person healthcare visits were reduced. Consequently, trial teams needed to consider implementing remote methods for conducting clinical trials, including e-Consent. Although so...
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Article
Open AccessIncidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria
Almost two million stillbirths occur annually, most occurring in low- and middle-income countries. Nigeria is reported to have one of the highest stillbirth rates on the African continent. The aim was to ident...
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Article
Open AccessAntibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries
Early development of the microbiome has been shown to affect general health and physical development of the infant and, although some studies have been undertaken in high-income countries, there are few studie...
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Article
Open AccessPrEP Use, Sexual Behaviour, and PrEP Adherence Among Men who have Sex with Men Living in Wales Prior to and During the COVID-19 Pandemic
We examined PrEP use, condomless anal sex (CAS), and PrEP adherence among men who have sex with men (MSM) attending sexual health clinics in Wales, UK. In addition, we explored the association between the intr...
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Article
Open AccessDevelopment of a core outcome set for the evaluation of interventions to enhance trial participation decisions on behalf of adults who lack capacity to consent: a mixed methods study (COnSiDER Study)
Trials involving adults who lack capacity to provide consent rely on proxy or surrogate decision-makers, usually a family member, to make decisions about participation. Interventions to enhance proxy decisions...
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Article
Open AccessA qualitative focus group study concerning perceptions and experiences of Nigerian mothers on stillbirths
To explore the experiences and perceptions of stillbirth among mothers from a tertiary medical centre in Kano, Northern Nigeria.
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Article
The Use of Posturography in Investigating the Risk of Falling in Frail or Prefrail Older People with Diabetes
In older people, diabetes is associated with an increased risk of falls and frailty. The value of using posturography for evaluating the risk of falling is unclear. In theory, a time-scale analysis should incr...
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Article
Frailty and Brain-Muscle Correlates in Older People With Type 2 Diabetes: A structural-MRI Explorative Study
Muscle alterations, mainly functional alterations are frequently observed in older people with type 2 diabetes (T2DM). Sarcopenia may be one mechanism of transition to frailty in these people. Thus, we aim to ...
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Article
Herkennen van pneumonie bij een hoestende patiënt: de klinische blik van de huisarts versus X‑thorax
Longontsteking wordt in de eerste lijn vaak empirisch behandeld, maar over de nauwkeurigheid van de klinische huisartsendiagnose is weinig bekend. Daarom hebben we gekeken naar de diagnostische nauwkeurigheid ...
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Article
Open AccessPragmatic trials of non-NHS interventions: experiences from a Randomised Controlled Trial of the Strengthening Families 10-14 UK Programme (SFP10-14 UK)
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Article
“I have always believed I was at high risk…” The role of expectation in emotional responses to the receipt of an average, moderate or high cancer genetic risk assessment result: a thematic analysis of free-text questionnaire comments
It is well-recognised that receipt of cancer genetic risk information can evoke a mix of both positive and negative emotional responses. Objective risk itself is not necessarily predictive of emotional respons...
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Article
Open AccessEen contextgebonden training voor huisartsen in communicatieve vaardigheden bij lageluchtweginfecties
Doel: Bepalen of een trainingsprogramma ter bevordering van de communicatieve vaardigheden van huisartsen bij lageluchtweginfecties, resulteert in de verwerving en handhaving van deze vaardighede...
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Article
Spleen but not tumor infiltration by dendritic and T cells is increased by intravenous adenovirus-Flt3 ligand injection
Dendritic cell (DC) expansion is regulated by the hematopoietic growth factor fms-like tyrosine kinase 3 ligand (Flt3L). DCs are critical to the control of tumor growth and metastasis, and there is a positive ...
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Article
Douglas-fir ectomycorrhizae in 40- and 400-year-old stands: mycobiont availability to late successional western hemlock
We investigated ectomycorrhizal (EM) fungi in forest stands containing both early successional Douglas-fir and late successional western hemlock at two points in the typical stand development by identifying EM...
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Article
Screening en het geven van informatie over persoonlijke risico’s
Achtergrond Er is weinig bekend over de wijze waarop voor- en nadelen van een screeningsprogramma het best besproken kunnen worden. Veel screeningsprogramma’s noemen gemiddelde risico’s in de discussie over deeln...
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Article
The development of a new site-specific measure of quality of life for breast problems: The Cardiff breast scales
The management of women presenting to primary care with symptoms of breast disease is of increasing interest given recent organisational changes aimed at improving accuracy and speed of referrals. As part of a...
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Article
On the latitudinal and radial motion of timelike vortical trajectories in the Kerr metric
The timelike vortical geodesies of the Kerr metric are integrated numerically in ther-θ subspace of the Boyer-Lindquist coordinates. We find that the trajectories, under physically reasonable conditions, are esse...
