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  1. Article

    Open Access

    Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade

    Tumor-infiltrating lymphocytes (TILs) have been associated with outcomes in HER2-positive breast cancer patients treated with neoadjuvant chemotherapy and trastuzumab. However, it remains unclear if TILs could...

    M. C. Liefaard, A. van der Voort, M. van Seijen, B. Thijssen in npj Breast Cancer (2024)

  2. Article

    Open Access

    Tumor characteristics of dissociated response to immune checkpoint inhibition in advanced melanoma

    Immune checkpoint inhibition (ICI) has improved patients’ outcomes in advanced melanoma, often resulting in durable response. However, not all patients have durable responses and the patients with dissociated ...

    J. M. Versluis, E. P. Hoefsmit, H. Shehwana in Cancer Immunology, Immunotherapy (2024)

  3. Article

    Open Access

    Improved calorimetric particle identification in NA62 using machine learning techniques

    Measurement of the ultra-rare K + → ...

    E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski in Journal of High Energy Physics (2023)

  4. Article

    Open Access

    A study of the K+ → π0e+νγ decay

    A sample of 1.3 × 105 K+π0e+νγ candidates with less than 1% background was collected by the NA62 experiment at the CERN SPS in 2017–2018. Branching fraction measurements are obtained at percent relative precis...

    E. Cortina Gil, A. Kleimenova, E. Minucci, S. Padolski in Journal of High Energy Physics (2023)

  5. Article

    Open Access

    Search for dark photon decays to μ+μ at NA62

    The NA62 experiment at CERN, designed to study the ultra-rare decay K+π+ ν ν ...

    E. Cortina Gil, J. Jerhot, A. Kleimenova, N. Lurkin in Journal of High Energy Physics (2023)

  6. Article

    Open Access

    BluePrint molecular subtypes predict response to neoadjuvant pertuzumab in HER2-positive breast cancer

    The introduction of pertuzumab has greatly improved pathological complete response (pCR) rates in HER2-positive breast cancer, yet effects on long-term survival have been limited and it is uncertain which pati...

    M. C. Liefaard, A. van der Voort, M. S. van Ramshorst, J. Sanders in Breast Cancer Research (2023)

  7. Article

    Open Access

    Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria

    Almost two million stillbirths occur annually, most occurring in low- and middle-income countries. Nigeria is reported to have one of the highest stillbirth rates on the African continent. The aim was to ident...

    Rebecca Milton, F. Modibbo, D. Gillespie, F. I. Alkali in BMC Pregnancy and Childbirth (2022)

  8. Article

    Open Access

    A qualitative focus group study concerning perceptions and experiences of Nigerian mothers on stillbirths

    To explore the experiences and perceptions of stillbirth among mothers from a tertiary medical centre in Kano, Northern Nigeria.

    R. Milton, F. I. Alkali, F. Modibbo, J. Sanders in BMC Pregnancy and Childbirth (2021)

  9. Article

    Correction: Management of nystagmus in children: a review of the literature and current practice in UK specialist services

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    J. E. Self, M. J. Dunn, J. T. Erichsen, I. Gottlob, H. J. Griffiths, C. Harris in Eye (2020)

  10. No Access

    Article

    Management of nystagmus in children: a review of the literature and current practice in UK specialist services

    Nystagmus is an eye movement disorder characterised by abnormal, involuntary rhythmic oscillations of one or both eyes, initiated by a slow phase. It is not uncommon in the UK and regularly seen in paediatric ...

    J. E. Self, M. J. Dunn, J. T. Erichsen, I. Gottlob, H. J. Griffiths, C. Harris in Eye (2020)

  11. Article

    Open Access

    Practical applications of studies on the TSH receptor and TSH receptor autoantibodies

    Studies on the TSH receptor (TSHR) have numerous practical applications in vitro and in vivo. For example human monoclonal autoantibodies (MAbs) to the TSHR are useful reagents for in vitro diagnostics. Measur...

    J. Furmaniak, J. Sanders, P. Sanders, J. Miller-Gallacher, M. M. Ryder in Endocrine (2020)

  12. Article

    Open Access

    Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study

    In colorectal cancer surgery there is a delicate balance between complete removal of the tumor and sparing as much healthy tissue as possible. Especially in rectal cancer, intraoperative tissue recognition cou...

    E. J. M. Baltussen, S. G. Brouwer de Koning in Journal of Translational Medicine (2019)

  13. Article

    Open Access

    Implementation of the Family Nurse Partnership programme in England: experiences of key health professionals explored through trial parallel process evaluation

    The Family Nurse Partnership (FNP) programme was introduced to support young first-time mothers. A randomised trial found FNP added little short-term benefit compared to usual care. The study included a compre...

    J. Sanders, Sue Channon, Nina Gobat, Kristina Bennert, Katy Addison in BMC Nursing (2019)

  14. Article

    SPECT/CT technology

    The continuous development of SPECT over the past 50 years has led to remarkably improved image quality and increased diagnostic confidence. The most influential developments include the realization of hybrid ...

    P. Ritt, J. Sanders, T. Kuwert in Clinical and Translational Imaging (2014)

  15. No Access

    Article

    3 ‘Human Leukocyte Antigen’ klasse 1-expressie in peniscarcinoom en relatie met klinische parameters

    Tumorcellen kunnen eigenschappen verwerven waarmee ze ontsnappen aan herkenning en vervolgens eliminatie door het immuunsysteem.

    R.S. Djajadiningrat, S. Horenblas, J. Sanders, J. de Jong in Tijdschrift voor Urologie (2014)

  16. No Access

    Article

    Enhanced sensitivity of the LIGO gravitational wave detector by using squeezed states of light

    Nearly a century after Einstein first predicted the existence of gravitational waves, a global network of Earth-based gravitational wave observatories1,2,3,4 is seeking to directly detect this faint radiation usi...

    J. Aasi, J. Abadie, B. P. Abbott, R. Abbott, T. D. Abbott in Nature Photonics (2013)

  17. Article

    Open Access

    The role of p21-activated kinase in the initiation of atherosclerosis

    p21-activated kinase (PAK) has been implicated in the inflammatory activation of endothelial cells by disturbed fluid shear stress, which is the initiating stimulus in atherosclerosis. The study addresses whet...

    K A Jhaveri, P Debnath, J Chernoff, J Sanders, M A Schwartz in BMC Cardiovascular Disorders (2012)

  18. Article

    Tissue oxygen saturation during anaesthesia, cardiopulmonary bypass and intensive care stay for cardiac surgery

    J Sanders, D Martin, A Smith, B Keogh, M Mutch, H Montgomery, M Hamilton in Critical Care (2008)

  19. No Access

    Article

    Autologous bone marrow transplantation for children with AML in first remission

    In Children's cancer group (CCG) 2891, newly diagnosed patients with AML were randomized between standard and intensive timing induction therapies. Patients in first remission who lacked an HLA matched family ...

    S Neudorf, J Sanders, N Kobrinsky, T A Alonzo, A Buxton in Bone Marrow Transplantation (2007)

  20. No Access

    Article

    Unravelling the genome: a review of molecular genetic research in schizophrenia

    Schizophrenia is a common and complex mental illness that affects approximately 1% of the population worldwide. Despite intensive research over the years, the aetiology and pathogenesis of schizophrenia is poo...

    J. Sanders, M. Gill in Irish Journal of Medical Science (2007)

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