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Article
Inflammation and the bone-vascular axis in end-stage renal disease
Bone loss and vascular calcification coincide in patients with end-stage renal disease, similar as to what is observed in the general population. In the present bone biopsy study, we provide further evidence t...
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Article
Retrospective observational study on the incidence of incisional hernias after colorectal carcinoma resection with follow-up CT scan
Incisional hernia (IH) is the most frequent complication after colorectal carcinoma (CRC) resection. The incidence depends on the method of follow-up, where ultrasound yields a significant number of additional...
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Article
Open AccessImpact of early parenteral nutrition on catabolism
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Chapter
Questioning the Pathogenic Role of the GLA p.Ala143Thr “Mutation” in Fabry Disease: Implications for Screening Studies and ERT
Fabry disease is an X-linked inborn error of glycosphingolipid metabolism caused by quantitative or qualitative defects in the lysosomal enzyme alfa-Galactosidase A (aGAL A), ultimately resulting in vital orga...
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Article
Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing
Despite extensive analysis of the BRCA1 and BRCA2 genes, germline mutations are detected in <20% of families with a presumed genetic predisposition for breast and ovarian cancer. Recent literature reported RAD51C
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Article
Open AccessMutation analysis of RAD51D in non-BRCA1/2 ovarian and breast cancer families
Recent data show that mutations in RAD51D have an aetiological role in ovarian carcinoma, yet mutations do not appear to be associated with an increased risk for breast cancer. We studied ovarian and breast cance...
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Article
Open AccessP14.07 Qtc Interval Duration is Associated with Vascular Calcification in Renal Transplant Candidates
Approximately 60% of all cardiac deaths in patients on dialysis are due to sudden death. Prolonged QT interval and arterial calcification have been associated with morbidity and mortality in different patient ...
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Article
Open AccessA replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort
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Article
Open AccessEvaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)
In this study we aimed to evaluate the role of a SNP in intron 1 of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast canc...
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Article
Bilateral renal cell carcinoma development in long-term Fabry disease
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Article
Open AccessBRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families
Worldwide variation in the distribution of BRCA1 and BRCA2 mutations is well recognised, and for the Belgian population no comprehensive studies about BRCA1/2 mutation spectra or frequencies have been published. ...
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Article
Open AccessChromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition
The chromosomal radiosensitivity of breast cancer patients with a known or putative genetic predisposition was investigated and compared to a group of healthy women. The chromosomal radiosensitivity was assess...
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Article
Double Prosthetic Valve Endocarditis Caused by Streptococcus pneumoniae
