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  1. No Access

    Article

    Clinical and socioeconomic impact of moderate-to-severe versus mild influenza in children

    Some studies have assessed the efficacy of influenza vaccination in children separately for moderate-to-severe and any influenza, but the definition used for identifying children with moderate-to-severe illnes...

    T. Heikkinen, H. Silvennoinen, S. Heinonen in European Journal of Clinical Microbiology … (2016)

  2. No Access

    Article

    A spatial equilibrium model of local nonmarket production with capacity constraints

    This paper studies the autonomous formation of regions with local nonmarket production in the presence of profit-maximizing producers. The approach is based on a spatial equilibrium model with a linear transpo...

    T. Heikkinen in International Review of Economics (2015)

  3. No Access

    Article

    A Hotelling model of spatial competition with local production

    Local production is a central theme in sustainable development and is of increasing current interest in e.g. food and energy production. This paper extends the classical Hotelling duopoly model of spatial comp...

    T. Heikkinen in Letters in Spatial and Resource Sciences (2014)

  4. Article

    Erratum to: Update with level 1 studies of the European Hernia Society guidelines on the treatment of inguinal hernia in adult patients

    M. Miserez, E. Peeters, T. Aufenacker, J. L. Bouillot, G. Campanelli, J. Conze in Hernia (2014)

  5. No Access

    Article

    A spatial economic model under network externalities: symmetric equilibrium and efficiency

    This paper studies a spatial economic model under network externalities, assuming a quadratic transport cost function. A classical circular model is applied where the consumers, each with a fixed demand, are u...

    T. Heikkinen in Operational Research (2014)

  6. Article

    Update with level 1 studies of the European Hernia Society guidelines on the treatment of inguinal hernia in adult patients

    In 2009, the European Hernia Society published the EHS Guidelines for the Treatment of Inguinal Hernia in Adult Patients. The Guidelines contain recommendations for the treatment of inguinal hernia from diagn...

    M. Miserez, E. Peeters, T. Aufenacker, J. L. Bouillot, G. Campanelli, J. Conze in Hernia (2014)

  7. Article

    Signs and symptoms predicting influenza in children: a matched case–control analysis of prospectively collected clinical data

    We aimed to determine whether there are signs or symptoms that could help clinicians to distinguish between influenza and other respiratory infections. The clinical data for this matched case–control analysis ...

    S. Heinonen, V. Peltola, H. Silvennoinen in European Journal of Clinical Microbiology … (2012)

  8. No Access

    Article

    Admission diagnoses of children 0–16 years of age hospitalized with influenza

    The prompt diagnosis of influenza enables the institution of antiviral therapy and adequate cohorting of patients, but scarce data are available to help clinicians correctly suspect influenza in children at th...

    H. Silvennoinen, V. Peltola, R. Vainionpää in European Journal of Clinical Microbiology … (2012)

  9. No Access

    Article

    Feasibility of diagnosing influenza within 24 hours of symptom onset in children 1–3 years of age

    Diagnosing influenza at an early stage of illness is important for the initiation of effective antiviral treatment. However, especially in young children, influenza often commences with an abrupt onset of feve...

    S. Heinonen, H. Silvennoinen, P. Lehtinen in European Journal of Clinical Microbiology … (2011)

  10. No Access

    Chapter and Conference Paper

    Multiuser Scheduling via Dynamic Optimization

    This paper studies optimal scheduling in a multiuser wireless network, allowing for simultaneous transmission of sets of users. The approach is based on dynamic optimization. The multiuser scheduling problem i...

    T. Heikkinen in Wired/Wireless Internet Communications (2010)

  11. Article

    Open Access

    Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)

    In this study we aimed to evaluate the role of a SNP in intron 1 of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast canc...

    A Osorio, R L Milne, G Pita, P Peterlongo, T Heikkinen in British Journal of Cancer (2009)

  12. Article

    Open Access

    European Hernia Society guidelines on the treatment of inguinal hernia in adult patients

    The European Hernia Society (EHS) is proud to present the EHS Guidelines for the Treatment of Inguinal Hernia in Adult Patients. The Guidelines contain recommendations for the treatment of inguinal hernia from...

    M. P. Simons, T. Aufenacker, M. Bay-Nielsen, J. L. Bouillot, G. Campanelli in Hernia (2009)

  13. No Access

    Article

    Functional comparison of the dynamic hip screw and the Gamma locking nail in trochanteric hip fractures: a matched-pair study of 268 patients

    The aim of this prospective matched-pair (age, sex, fracture type, residential status, and walking ability at fracture) study was to analyse the short-term outcome after Gamma nail (GN) and dynamic hip screw (...

    I. Saarenpää, T. Heikkinen, J. Ristiniemi, P. Hyvönen in International Orthopaedics (2009)

  14. Article

    Open Access

    An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers

    The close functional relationship between p53 and the breast cancer susceptibility genes BRCA1 and BRCA2 has promoted the investigation of various polymorphisms in the p53 gene as possible risk modifiers in BRCA1...

    A Osorio, M Pollán, G Pita, R K Schmutzler, B Versmold in British Journal of Cancer (2008)

  15. No Access

    Article

    Treatment of subtrochanteric fractures. A comparison of the Gamma nail and the dynamic hip screw: short-term outcome in 58 patients

    The aim of this non-randomised prospective study was to evaluate the short-term outcome of Gamma nail and dynamic hip screw (DHS) fixation in the treatment of subtrochanteric hip fractures due to low-energy tr...

    I. Saarenpää, T. Heikkinen, P. Jalovaara in International Orthopaedics (2007)

  16. No Access

    Article

    Early results of a randomised trial comparing Prolene and VyproII-mesh in endoscopic extraperitoneal inguinal hernia repair (TEP) of recurrent unilateral hernias

    The purpose of this study was to compare a lightweight mesh to a standard polypropylene hernia mesh in endoscopic extraperitoneal hernioplasty in recurrent hernias. A total of 140 men with recurrent unilateral...

    T. Heikkinen, S. Wollert, J. Österberg, S. Smedberg, S. Bringman in Hernia (2006)

  17. No Access

    Article

    One year results of a randomised controlled multi-centre study comparing Prolene and Vypro II-mesh in Lichtenstein hernioplasty

    A standard polypropylene mesh used in Lichtenstein’s operation induces a strong foreign tissue reaction with potential harmful effects. A mesh with less polypropylene could possibly be beneficial. Six hundred ...

    S. Bringman, S. Wollert, J. Österberg, S. Smedberg, H. Granlund, G. Felländer in Hernia (2005)

  18. No Access

    Article

    Early results of a randomized multicenter trial comparing Prolene and VyproII mesh in bilateral endoscopic extraperitoneal hernioplast (TEP)

    The use of mesh in inguinal hernia surgery has become increasingly popular despite the potentially harmful effects that foreign material may exert on human tissue. The purpose of this study was to compare the ...

    S. Bringman, S. Wollert, J. Osterberg in Surgical Endoscopy And Other Interventiona… (2005)

  19. No Access

    Article

    The quality of life of gastroesophageal reflux disease patients waiting for an antireflux operation

    The purpose of this trial was to measure the health-related quality of life (HRQL) of gastroesophageal reflux disease (GERD) patients waiting for an antireflux operation.

    T. Heikkinen, V. Koivukangas, H. Wiik, J. Saarnio, T. Rautio in Surgical Endoscopy (2004)

  20. No Access

    Article

    Distributed Scheduling and Dynamic Pricing in a Communication Network

    This paper studies dynamic resource allocation in a decentralized communication network. The temporal aspect in the decentralized resource allocation problem presents new challenges, e.g., in optimizing the de...

    T. Heikkinen in Wireless Networks (2004)

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