Skip to main content

9 Result(s)

within Joydeb Kumar Kundu Remove this filter

and

  1. Article

    Open Access

    Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

    Blockade of the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction has emerged as a powerful strategy in cancer immunotherapy. Recently, there have been enormous efforts to devel...

    Aravindhan Ganesan, Marawan Ahmed, Isobel Okoye, Elena Arutyunova… in Scientific Reports (2019)

    Download PDF (4357 KB) View Article

  2. No Access

    Article

    Targeting ROCK/LIMK/cofilin signaling pathway in cancer

    Rho-associated coiled-coil-containing protein kinase (ROCK)/Lin11, Isl-1 and Mec-3 kinase (LIMK)/cofilin-signaling cascades are stimulated by receptor tyrosine kinases, G protein-coupled receptors, integrins a...

    Mee-Hyun Lee, Joydeb Kumar Kundu, Jung-Il Chae… in Archives of Pharmacal Research (2019)

  3. No Access

    Article

    Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1

    The present study was aimed at elucidating the molecular mechanisms of anti-inflammatory activity of piceatannol (trans-3,4,3′,5′-tetrahydroxystilbene) in mouse skin in vivo.

    Lijia Liu, Jianchun Li, Joydeb Kumar Kundu, Young-Joon Surh in Inflammation Research (2014)

  4. No Access

    Chapter

    Molecular Mechanisms of Chemoprevention with Capsaicinoids from Chili Peppers

    Chemoprevention is one of the most practical strategies to prevent cancer. Numerous dietary phytochemicals present in fruits, vegetables and spices have been reported to possess cancer preventive properties. C...

    Young-Joon Surh, Joydeb Kumar Kundu in Vegetables, Whole Grains, and Their Deriva… (2011)

  5. No Access

    Article

    Nrf2-Keap1 Signaling as a Potential Target for Chemoprevention of Inflammation-Associated Carcinogenesis

    Persistent inflammatory tissue damage is causally associated with each stage of carcinogenesis. Inflammation-induced generation of reactive oxygen species, reactive nitrogen species, and other reactive species...

    Joydeb Kumar Kundu, Young-Joon Surh in Pharmaceutical Research (2010)

  6. No Access

    Article

    Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress

    Nitrosative stress caused by reactive nitrogen species such as nitric oxide and peroxynitrite overproduced during inflammation leads to cell death and has been implicated in the pathogenesis of many human ailm...

    Young-Joon Surh, Joydeb Kumar Kundu, Mei-Hua Li… in Archives of Pharmacal Research (2009)

  7. No Access

    Article

    Molecular basis of chemoprevention with dietary phytochemicals: redox-regulated transcription factors as relevant targets

    A precise regulation of redox balance is required for the cellular homeostatic control. Aberrant activation of redox-sensitive transcription factors, such as nuclear factor-kappaB (NF-κB), activator protein 1 ...

    Joydeb Kumar Kundu, Young-Joon Surh in Phytochemistry Reviews (2009)

  8. No Access

    Article

    [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin

    [6]-Gingerol, a pungent ingredient of ginger (Zingiber officinale Roscoe, Zingiberaceae), has a wide array of pharmacologic effects. The present study was aimed at unraveling the molecular mechanisms underlying p...

    Sue Ok Kim, Joydeb Kumar Kundu, Young Kee Shin, **-Hong Park, Myung-Haing Cho… in Oncogene (2005)

  9. No Access

    Article

    Signal transduction network leading to COX-2 Induction: a road map in search of cancer chemopreventives

    Cancer is still a major global health concern even after an everlasting strive in conquering this dread disease. Emphasis is now given to chemoprevention to reduce the risk of cancer and also to improve the qu...

    Young-Joon Surh, Joydeb Kumar Kundu in Archives of Pharmacal Research (2005)