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  1. Article

    Open Access

    Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody

    The blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor mediated transport systems, such as the transferrin receptor, can be used...

    Thomas J. Esparza, Shiran Su, Caroline M. Francescutti… in Fluids and Barriers of the CNS (2023)

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  2. No Access

    Article

    Axonal disruption in white matter underlying cortical sulcus tau pathology in chronic traumatic encephalopathy

    Chronic traumatic encephalopathy (CTE) is a progressive degenerative disorder associated with repetitive traumatic brain injury. One of the primary defining neuropathological lesions in CTE, based on the first...

    Laurena Holleran, Joong Hee Kim, Mihika Gangolli, Thor Stein… in Acta Neuropathologica (2017)

  3. No Access

    Article

    Diffusion tensor imaging of the mouse brainstem and cervical spinal cord

    Concurrent and/or progressive degeneration of upper and lower motor neurons (LMNs) causes neurological symptoms and dysfunctions in motor neuron diseases (MNDs) such as amyotrophic lateral sclerosis (ALS). Alt...

    Joong Hee Kim, Sheng-Kwei Song in Nature Protocols (2013)

  4. Article

    Open Access

    CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed by in vivoaxial diffusivity

    Multiple Sclerosis (MS) is characterized by the pathological trafficking of leukocytes into the central nervous system (CNS). Using the murine MS model, experimental autoimmune encephalomyelitis (EAE), we prev...

    Lillian Cruz-Orengo, Ying-Jr Chen, Joong Hee Kim… in Journal of Neuroinflammation (2011)

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