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Article
Open AccessPatient reported and functional outcome measures after surgical salvage procedures for posttraumatic radiocarpal osteoarthritis – a systematic review
Posttraumatic wrist osteoarthritis is an irreversible and often progressive condition. Many surgical treatments, used in (daily) practice, aim to relieve symptoms like pain and restore function. The aim of thi...
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Article
Open AccessPolytherapy versus monotherapy in the treatment of tibial non-unions: a retrospective study
Treating tibial non-unions efficiently presents a challenge for orthopaedic trauma surgeons. The established gold standard involves implanting autologous bone graft with adequate fixation, but the addition of ...
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Article
Open AccessEffectiveness of permissive weight bearing in surgically treated trauma patients with peri- and intra-articular fractures of the lower extremities: a prospective comparative multicenter cohort study
The aim of the present study was to investigate the effectiveness of a novel approach involving permissive weight bearing (PWB) in surgically treated trauma patients with peri- and intra-articular fractures of...
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Article
Open AccessSurgical suction filter-derived bone graft displays osteogenic miRNA and mRNA patterns
Recently, a surgical suction filter device was introduced which aims at generating a suction filter-derived bone grafting substitute (SF-BGS). The osteogenic capacity of this grafting material, however, is unc...
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Article
Open AccessAre the non-weight bearing guidelines for the after treatment of calcaneal fractures still decisive? A Dutch survey among orthopaedic and trauma surgeons
The current rehabilitation for patients with surgically treated displaced intra-articular calcaneal fractures (DIACFs) consists of non-weightbearing for 8–12 weeks. The purpose of the present survey was to inv...
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Article
Open AccessAlignment of CCI total ankle replacements in relation to midterm functional outcome and complication incidence
Total ankle arthroplasty is increasingly used as a treatment for end stage ankle arthropathy. The aim of this study was to report the mid-term clinical function and survival results of Ceramic Coated Implant (...
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Article
Open AccessThe effect of perturbation-based balance training on balance control and fear of falling in older adults: a single-blind randomised controlled trial
Perturbation-based balance training (PBT) is an emerging intervention shown to improve balance recovery responses and reduce falls in everyday life in older adults. However, perturbation interventions were het...
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Article
Open AccessThe influence of inter-hospital transfers on mortality in severely injured patients
The importance of treating severely injured patients in higher-level trauma centers is undisputable. However, it is uncertain whether severely injured patients that were initially transported to a lower-level ...
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Article
Severe isolated injuries have a high impact on resource use and mortality: a Dutch nationwide observational study
The Berlin poly-trauma definition (BPD) has proven to be a valuable way of identifying patients with at least a 20% risk of mortality, by combining anatomical injury characteristics with the presence of physio...
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Article
Open AccessThe impact of regionalized trauma care on the distribution of severely injured patients in the Netherlands
Twenty years ago, an inclusive trauma system was implemented in the Netherlands. The goal of this study was to evaluate the impact of structured trauma care on the concentration of severely injured patients ov...
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Article
Open AccessPriority accuracy by dispatch centers and Emergency Medical Services professionals in trauma patients: a cohort study
Priority-setting by dispatch centers and Emergency Medical Services professionals has a major impact on pre-hospital triage and times of trauma patients. Patients requiring specialized care benefit from expedi...
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Article
Open AccessRisk factors of non-union in intramedullary stabilized diaphyseal long bone fractures: identifying the role of fracture stabilization strategies and concomitant injuries
Concomitant chest injury is known to negatively affect bone metabolism and fracture healing, whereas traumatic brain injury (TBI) appears to have positive effects on bone metabolism. Osteogenesis can also be i...
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Article
Open AccessSample preparation of bone tissue for MALDI-MSI for forensic and (pre)clinical applications
In the past decades, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has been applied to a broad range of biological samples, e.g., forensics and preclinical samples. The use ...
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Article
Open AccessPerturbation-based balance training to improve balance control and reduce falls in older adults – study protocol for a randomized controlled trial
Falls are a common cause of injuries and hospitalization among older adults. While conventional balance training appears effective in preventing falls, a relatively large number of training sessions are needed...
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Article
Open AccessThe impact of the Trauma Triage App on pre-hospital trauma triage: design and protocol of the stepped-wedge, cluster-randomized TESLA trial
Field triage of trauma patients is crucial to get the right patient to the right hospital within a particular time frame. Minimization of undertriage, overtriage, and interhospital transfer rates could substan...
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Article
Open AccessThe cutaneous microbiome in hospitalized patients with pressure ulcers
This study investigated whether there are differences in the composition of the cutaneous microbiome of the unaffected skin between patients with pressure ulcers compared with those without pressure ulcers. Th...
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Article
Incidence of post-traumatic pneumonia in poly-traumatized patients: identifying the role of traumatic brain injury and chest trauma
Traumatic brain injury (TBI) and chest trauma are common injuries in severely injured patients. Both entities are well known to be associated with severe post-traumatic complications, including pneumonia, a co...
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Article
Open AccessDevelopment of a novel murine delayed secondary fracture healing in vivo model using periosteal cauterization
Delayed union and nonunion development remain a major clinical problematic complication during fracture healing, with partially unclear pathophysiology. Incidences range from 5 to 40% in high-risk patients, su...
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Article
The role of the Fracture Liaison Service (FLS) in subsequent fracture prevention in the extreme elderly
Several guidelines recommend a bone and fall-related osteoporosis risk assessment in all patients with fracture and age > 50 years. In practice, however, there is no consensus whether screening > 85 years is u...
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Article
Open AccessEffect of neurokinin-1-receptor blockage on fracture healing in rats
Neurologic injury and selective blockage of sensory nerve endings is associated with impaired fracture healing, however, the role of specific neurotransmitters has not been sufficiently investigated. Our aim w...
