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Article
Open AccessLong-term diosmectite use does not alter the gut microbiota in adults with chronic diarrhea
Diosmectite, a natural colloidal clay, has been used worldwide for a number of approved indications, including the treatment of chronic functional diarrhea. Here, we used high-resolution whole metagenome shotg...
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Article
Open AccessLate weaning is associated with increased microbial diversity and Faecalibacterium prausnitzii abundance in the fecal microbiota of piglets
In pig production systems, weaning is a crucial period characterized by nutritional, environmental, and social stresses. Piglets transition from a milk-based diet to a solid, more complex plant-based diet, and...
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Article
Correction: Amendments: Author Correction: A catalog of the mouse gut metagenome
Nat. Biotechnol. 33, 1103–1108 (2015); published online 28 September 2015; corrected after print 18 December 2018 In the version of this article initially published, the y-axis numbering in Figure 1 was high b...
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Article
Prediction of the intestinal resistome by a three-dimensional structure-based method
The intestinal microbiota is considered to be a major reservoir of antibiotic resistance determinants (ARDs) that could potentially be transferred to bacterial pathogens via mobile genetic elements. Yet, this ...
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Chapter
Human Gut Metagenomics: Success and Limits of the Activity-Based Approaches
The symbiotic relationship between the host and its gut microbiota has evolved to benefit both parties, especially by maintaining the host health and providing nutrients to the microbiota. Until recently, the ...
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Article
A reference gene catalogue of the pig gut microbiome
The pig is a major species for livestock production and is also extensively used as the preferred model species for analyses of a wide range of human physiological functions and diseases1. The importance of the g...
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Article
Transcriptional interactions suggest niche segregation among microorganisms in the human gut
The human gastrointestinal (GI) tract is the habitat for hundreds of microbial species, of which many cannot be cultivated readily, presumably because of the dependencies between species1. Studies of microbial co...
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Article
A catalog of the mouse gut metagenome
The mouse gut microbiome is catalogued and compared to the human microbiome.
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Reference Work Entry In depth
Functional Metagenomics of Human Intestinal Microbiome β-Glucuronidase Activity
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Reference Work Entry In depth
Functional Metagenomics of Bacterial-Cell Crosstalk
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Article
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
Sequencing the microbial species present in complex metagenomic samples is made easier with a method that groups genes by co-abundance.
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Article
Metagenomic species profiling using universal phylogenetic marker genes
A method and software for profiling microbial communities from shotgun sequence data uses universal single-copy marker sequences for accurate species-level assignment. The method can classify species lacking a...
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Article
Translating the human microbiome
Nine experts discuss the challenges in translating current research on the human microbiome into strategies for disease prediction, diagnosis and therapy.
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Living Reference Work Entry In depth
Functional Metagenomics of Human Intestinal Microbiome β-Glucuronidase Activity
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Living Reference Work Entry In depth
Functional Metagenomics of Bacterial-Cell Crosstalk
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Article
Open AccessAn iterative workflow for mining the human intestinal metaproteome
Peptide spectrum matching (PSM) is the standard method in shotgun proteomics data analysis. It relies on the availability of an accurate and complete sample proteome that is used to make interpretation of the ...
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Article
Open AccessComposition of human intestinal flora analysed by fluorescent in situ hybridisation using group-specific 16S rRNA-targeted oligonucleotide probes
Cultivation methods classically used to describe the faecal flora composition are often too selective for certain groups of bacteria. This study was conducted to determine the human faecal flora composition by...
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Article
Culture-independent characterisation of human faecal flora using rRNA-targeted hybridisation probes
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Article
Diversity of H2/CO2-Utilizing Acetogenic Bacteria from Fecesof Non-Methane-Producing Humans
The purpose of this work was to study H2/CO2-utilizing acetogenic population in the colons of non-methane-producing individuals harboring low numbers of methanogenic archaea. Among the 50 H2-consuming acetogenic...
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Chapter
One-Carbon Metabolism by the Rumen Acetogen Syntrophococcus Sucromutans
The rumen acetogen Syntrophococcus sucromutans has an absolute requirement for an electron acceptor system to catabolize a variety of carbohydrates as electron donors 1. It can use the O-demethylation of lignin-d...