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  1. Article

    Open Access

    RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum

    The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can ...

    **nglin Zhang, Vincent de Maat, Ana M. Guzmán Prieto, Tomasz K. Prajsnar in BMC Genomics (2017)

  2. Article

    Open Access

    From transcriptional landscapes to the identification of biomarkers for robustness

    The ability of microorganisms to adapt to changing environments and gain cell robustness, challenges the prediction of their history-dependent behaviour. Using our model organism Bacillus cereus, a notorious Gram...

    Tjakko Abee, Michiel Wels, Mark de Been, Heidy den Besten in Microbial Cell Factories (2011)

  3. Article

    Open Access

    An iterative workflow for mining the human intestinal metaproteome

    Peptide spectrum matching (PSM) is the standard method in shotgun proteomics data analysis. It relies on the availability of an accurate and complete sample proteome that is used to make interpretation of the ...

    Koos Rooijers, Carolin Kolmeder, Catherine Juste, Joël Doré, Mark de Been in BMC Genomics (2011)

  4. No Access

    Article

    Silencing of the pollen-specific gene NTP303 and its family members in tobacco affects in vivo pollen tube growth and results in male sterile plants

    In seed plants, successful fertilization requires correct regulation of pollen tube growth. At germination and during growth, the pollen tube interacts with tissues from the pistil while the pollen tube extend...

    Peter de Groot, Koen Weterings, Mark de Been, Floyd Wittink in Plant Molecular Biology (2004)

  5. No Access

    Chapter

    Silencing of the Pollen Gene NTP303 Ceases Pollen Tube Growth in Vivo in Nicotiana tabacum

    The main objective of our study is the elucidation of the molecular and physiological basis for the role of the male reproductive organ, the pollen grain or gametophyte, in the process of fertilization. Althou...

    George J. Wullems, Peter F. M. de Groot in Plant Biotechnology 2002 and Beyond (2003)