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Article
Open AccessAgomir-122-loaded nanoparticles coated with cell membrane of activated fibroblasts to treat frozen shoulder based on homologous targeting
As a common musculoskeletal disorder, frozen shoulder is characterized by thickened joint capsule and limited range of motion, affecting 2–5% of the general population and more than 20% of patients with diabet...
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Article
Anterior cruciate ligament femoral footprint is oblong-ovate, triangular, or two-tears shaped in healthy young adults: three-dimensional MRI analysis
This study aimed to evaluate the morphology of the anterior cruciate ligament (ACL) femoral footprint with three-dimensional magnetic resonance imaging (3D MRI) in healthy knees.
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Article
Open Accesssi-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitis
Adhesive capsulitis is a common shoulder disorder inducing joint capsule fibrosis and pain. When combined with rotator cuff tear (RCT), treatments can be more complex. Currently, targeted therapy is lacking. S...
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Chapter
Basic Concepts in the Treatment of Knee Dislocation
Knee dislocation refers to the disorder of the articulation of the tibia and the femur, which is a spatial concept and time-sensitive (has been or is in the state of dislocation). The anatomical structure diso...
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Chapter
Basic Concepts in Revision Anterior Cruciate Ligament Reconstruction
In recent 10 years, anterior cruciate ligament (ACL) reconstruction surgery has been rapidly popularized, and the total number of patients undergoing reconstruction has increased significantly. However, more a...
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Article
Open AccessTranscriptome analysis reveals the encystment-related lncRNA expression profile and coexpressed mRNAs in Pseudourostyla cristata
Ciliated protozoans form dormant cysts for survival under adverse conditions. The molecular mechanisms regulating this process are critical for understanding how single-celled eukaryotes adapt to the environme...
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Article
Open AccessNovel insights into molecular mechanisms of Pseudourostyla cristata encystment using comparative transcriptomics
The encystment of many ciliates is an advanced survival strategy against adversity and the most important reason for ciliates existence worldwide. However, the molecular mechanism for the encystment of free-li...
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Article
Double-row rotator cuff repairs lead to more intensive pain during the early postoperative period but have a lower risk of residual pain than single-row repairs
The purpose of this study is to compare pain patterns and identify factors associated with residual shoulder pain after rotator cuff repairs using double-row and single-row techniques.
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Management of Irreparable Rotator Cuff Tear: Arthroscopy-Assisted Latissimus Dorsi Tendon Transfer
Latissimus dorsi tendon (LDT) transfer, first introduced into practice for the treatment of massive rotator cuff tear in 1988, is becoming increasingly popular recently. Both short- and long-term follow-up res...
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Article
Open AccessNew contribution to the morphology and molecular mechanism of Euplotes encysticus encystment
Ciliated protists are a large group of single-cell eukaryotes, leading to the resting cysts in unfavorable environmental condition. However, the underlying molecular mechanism of encystment in the free-living ...
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Article
MRI-based ACL graft maturity does not predict clinical and functional outcomes during the first year after ACL reconstruction
To determine whether magnetic resonance image (MRI)-based graft maturity predicts clinical and functional scores during the first year after ACL reconstruction.
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Article
Identification of cyst wall proteins of the hypotrich ciliate Euplotes encysticus using a proteomics approach
Euplotes encysticus is a species of Hypotrich ciliates, which form cyst wall by secreting the special substances on encounter of adverse environment. It has critical significance ...
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Article
Effect of centre-edge angle on clinical and quality of life outcomes after arthroscopic acetabular labral debridement
The aim of this study was to compare clinical and quality of life outcomes following arthroscopic acetabular labral debridement between patients with different centre-edge (CE) angle.
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Article
Open AccessThe REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
Increasing incidence of inflammatory bowel disorders demands a better understanding of the molecular mechanisms underlying its multifactorial aetiology. Here we demonstrate that mice deficient for REGγ, a prot...
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Article
Open AccessCorrection: Corrigendum: Large-scale identification of encystment-related proteins and genes in Pseudourostyla cristata
The transformation of a ciliate into cyst is an advance strategy against an adverse situation. However, the molecular mechanism for the encystation of free-living ciliates is poorly understood. A large-scale i...
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Article
Open AccessLarge-scale identification of encystment-related proteins and genes in Pseudourostyla cristata
The transformation of a ciliate into cyst is an advance strategy against an adverse situation. However, the molecular mechanism for the encystation of free-living ciliates is poorly understood. A large-scale i...
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Article
Comparison of tendon–bone healing between autografts and allografts after anterior cruciate ligament reconstruction using magnetic resonance imaging
The purpose of the study is to compare tendon–bone healing between autograft tendons and allograft tendons after anterior cruciate ligament (ACL) reconstruction using 3.0T magnetic resonance imaging.
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Chapter
The Role of Arthroscopic Capsular Release
“Primary frozen shoulder syndrome” or simply “frozen shoulder” constitutes a self-limited disorder and, therefore, conservative treatment should be the first treatment option. After failing a well-supervised, ...
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Article
Open AccessDifferential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells
Proteasome activity is frequently enhanced in cancer to accelerate metastasis and tumorigenesis. REGγ, a proteasome activator known to promote p53/p21/p16 degradation, is often overexpressed in cancer cells. H...
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Article
Open AccessREGγ is associated with multiple oncogenic pathways in human cancers
Recent studies suggest a role of the proteasome activator, REGγ, in cancer progression. Since there are limited numbers of known REGγ targets, it is not known which cancers and pathways are associated with REGγ.
