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Article
Sustainable synthesis of hierarchical porous N, O-codoped carbon nanorods with pseudocapacitance contribution for lithium-ion battery anodes and supercapacitors
A green and sustainable approach was employed to synthesize N, O-codoped porous carbon nanorods with two-end-open characteristics. In this method, a crab shell was utilized as a template and activator, while e...
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Article
Open AccessEstablishment of CRISPR-Cas9 system in Bifidobacteria animalis AR668
Bifidobacteria are representative intestinal probiotics that have extremely high application value in the food and medical fields. However, the lack of molecular biology tools limits the research on functional ge...
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Article
Complete Genome Sequence of Lactobacillus salivarius AR809, a Probiotic Strain with Oropharyngeal Tract Resistance and Adhesion to the Oral Epithelial Cells
Lactobacillus salivarius AR809 was isolated from a healthy adult oral cavity with multiple probiotic properties, such as high antimicrobial activity, adhesion to the oral epithelium, resistance to acidic pH, bile...
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Article
Open AccessMicrobial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Emerging research supports that triclosan (TCS), an antimicrobial agent found in thousands of consumer products, exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models. While the ...
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Article
Open AccessDisease burden and prognostic factors for clinical failure in elderly community acquired pneumonia patients
The study was to evaluate initial antimicrobial regimen and clinical outcomes and to explore risk factors for clinical failure (CF) in elderly patients with community-acquired pneumonia (CAP).
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Article
Enhancement of antroquinonol and antrodin C productions via in situ extractive fermentation of Antrodia camphorata S-29
This study describes the application of in situ extractive fermentation (ISEF) to increase the yields of antroquinonol (AQ) and antrodin C (AC) from Antrodia camphorata S-29. In initial screening experiments, nin...
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Article
Open AccessNon-saturating quantum magnetization in Weyl semimetal TaAs
Detecting the spectroscopic signatures of relativistic quasiparticles in emergent topological materials is crucial for searching their potential applications. Magnetometry is a powerful tool for fathoming elec...
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Article
Open AccessA megawatt-level surface wave oscillator in Y-band with large oversized structure driven by annular relativistic electron beam
High power vacuum electronic devices of millimeter wave to terahertz regime are attracting extensive interests due to their potential applications in science and technologies. In this paper, the design and exp...
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Article
Open AccessEffects of age, comorbidity and adherence to current antimicrobial guidelines on mortality in hospitalized elderly patients with community-acquired pneumonia
Limited information exists on the clinical characteristics predictive of mortality in patients aged ≥65 years in many countries. The impact of adherence to current antimicrobial guidelines on the mortality of ...
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Article
Coal price fluctuation mechanism in China based on system dynamics model
We analyze and identify the factors that influence coal price fluctuations and construct a system dynamics model of these factors. The simulation results show that the trend in China’s future coal prices first...
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Article
Solid-state fermentation with Serratia marcescens Xd-1 enhanced production of prodigiosin by using bagasse as an inertia matrix
Prodigiosin has attracted great interest for several decades for its proapoptotic anticancer and other activities. However, the low productivity of prodigiosin under submerged fermentation (SmF) limits its com...
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Article
Use of a Novel Report Protein to Study the Secretion Signal of Flagellin in Bacillus subtilis
Flagellin (also called Hag) is the main component of bacterial flagellum and is transported across the cytoplasmic membrane by flagellar secretion apparatus. Because flagella play an essential role in the path...
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Article
Open AccessDiagnosis of a malayan filariasis case using a shotgun diagnostic metagenomics assay
Malayan filariasis is a lymphatic filariasis caused by Brugia malayi. It is easily misdiagnosed in non-endemic areas for atypical symptoms and rare diagnostic experience. A 34-year-old Chinese woman in New York p...
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Article
Common Non-classically Secreted Bacterial Proteins with Experimental Evidence
The non-classically secreted proteins are the proteins that are located in the extracellular milieu despite the absence of known signal peptides or other targeting peptides. Numerous experimental studies have ...
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Article
Open AccessA new potential secretion pathway for recombinant proteins in Bacillus subtilis
Secretion of cytoplasmic expressed proteins into growth media has significant advantages. Due to the lack of an outer membrane, Bacillus subtilis is considered as a desirable ‘cell factory’ for the secretion of r...
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Article
How are the Non-classically Secreted Bacterial Proteins Released into the Extracellular Milieu?
Most bacterial proteins that are destined to leave the cytoplasm are exported across the cell membrane to their sites of function. These proteins are generally exported via the classical secretion pathway, in ...
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Article
The Secretion of an Intrinsically Disordered Protein with Different Secretion Signals in Bacillus subtilis
In this study, a naturally unsecretory intrinsically disordered domain of nucleoskeletal-like protein (Nsp) was attempted to be secreted with different types of secretion signals in Bacillus subtilis. The results...
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Article
Open AccessREGγ is associated with multiple oncogenic pathways in human cancers
Recent studies suggest a role of the proteasome activator, REGγ, in cancer progression. Since there are limited numbers of known REGγ targets, it is not known which cancers and pathways are associated with REGγ.
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Article
Regulation of REGγ cellular distribution and function by SUMO modification
Discovery of emerging REGγ-regulated proteins has accentuated the REGγ-proteasome as an important pathway in multiple biological processes, including cell growth, cell cycle regulation, and apoptosis. However,...
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Article
Electrochemical sensor of nitrite based on an inorganic film modified glassy carbon electrode
The electrocatalysis of nitrite in solutions at an inorganic film modified glassy carbon electrode was studied. The modifier was an electrodeposited thin inorganic film of the copper-heptacyanonitrosylferrate ...