44 Result(s)

Article

Correction: Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress

Chen-Yue Liu, Jian-Bei Chen, Yue-Yun Liu, Xue-Ming Zhou, Man Zhang… in Chinese Medicine (2023)

Article

Retraction Note: Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of **ao Yao san on chronically stressed mice

**u-Fang Ding, Yue-Hua Li, Jia-Xu Chen… in BMC Complementary Medicine and Therapies (2023)

Article

Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress

Many studies about depression have focused on the dysfunctional synaptic signaling in the hippocampus that drives the pathophysiology of depression. Radix Bupleuri has been used in China for over 2000 years to re...

Chen-Yue Liu, Jian-Bei Chen, Yue-Yun Liu, Xue-Ming Zhou, Man Zhang… in Chinese Medicine (2022)

Article

m6A modification: recent advances, anticancer targeted drug discovery and beyond

Abnormal N6-methyladenosine (m6A) modification is closely associated with the occurrence, development, progression and prognosis of cancer, and aberrant m6A regulators have been identified as novel anticancer ...

Li-Juan Deng, Wei-Qing Deng, Shu-Ran Fan, Min-Feng Chen, Ming Qi… in Molecular Cancer (2022)

Article

Efficacy and safety of **aoyao pills for mild to moderate depression: study protocol for a randomized controlled trial

Depression is one of the most frequent and severe psychiatric conditions. Many chemical drugs to treat depression are associated with adverse reactions and have shortcomings. Traditional Chinese medicine is of...

Zhe Xue, Zhen Huang, Shu-li Cheng, **-hong Wang, Xuan Zhou, Qing-yu Ma… in Trials (2022)

Article

MicroRNA-497 induced by Clonorchis sinensis enhances the TGF-β/Smad signaling pathway to promote hepatic fibrosis by targeting Smad7

Various stimuli, including Clonorchis sinensis infection, can cause liver fibrosis. Liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs) with massive production of extracellular matr...

Qian-Yang Zhou, Hui-Min Yang, Ji-**n Liu, Na Xu, **g Li… in Parasites & Vectors (2021)

Article

Risk factors for Blastocystis infection in HIV/AIDS patients with highly active antiretroviral therapy in Southwest China

Blastocystis is a widespread zoonotic protozoan of mammalian species, especially in HIV/AIDS individuals. The aim of this study was to analyze the prevalence and risk factors related with Blastocystis infection a...

Shun-**an Zhang, Fen-Yan Kang, Jia-Xu Chen, Li-Guang Tian… in Infectious Diseases of Poverty (2019)

Article

**aoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

Mounting evidence indicates that the cerebral cortex is an important physiological system of emotional activity, and its dysfunction may be the main cause of stress. Glutamate is the primary excitatory neurotr...

Yan Liu, **u-fang Ding, **n-xing Wang… in BMC Complementary and Alternative Medicine (2019)

Article

Arenobufagin induces MCF-7 cell apoptosis by promoting JNK-mediated multisite phosphorylation of Yes-associated protein

It has been demonstrated that bufadienolides exert potent anti-cancer activity in various tumor types. However, the mechanisms that underlie their anti-cancer properties remain unclear. Yes-associated protein,...

Li-Juan Deng, Ming Qi, Qun-Long Peng, Min-Feng Chen, Qi Qi… in Cancer Cell International (2018)

Article

Screening for biomarkers reflecting the progression of Babesia microti infection

Babesiosis is caused by the invasion of erythrocytes by parasites of the Babesia spp. Babesia microti is one of the primary causative agents of human babesiosis. To better understand the status of the disease, di...

Bin Xu, **u-Feng Liu, Yu-Chun Cai, Ji-Lei Huang, Rui-**ang Zhang… in Parasites & Vectors (2018)

Article

Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania

Human African trypanosomiasis (HAT) is one of the most complex parasitic diseases known to humankind. It usually occurs in endemic areas in Africa, but is occasionally detected in returning travelers and migra...

Qin Liu, **ao-Ling Chen, Mu-**n Chen, Han-Guo **e… in Infectious Diseases of Poverty (2018)

Article

Antibiotic resistance and molecular characterization of diarrheagenic Escherichia coli and non-typhoidal Salmonella strains isolated from infections in Southwest China

Bacterial diarrhea is one of the most common causes for medical consultations, mortality and morbidity in the world. Diarrheagenic Escherichia coli (DEC) and non-typhoidal Salmonella (NTS) are major intestinal pa...

Shun-**an Zhang, Yong-Ming Zhou, Li-Guang Tian… in Infectious Diseases of Poverty (2018)

Article

Performance evaluation of existing immunoassays for Clonorchis sinensis infection in China

Clonorchiasis ranks among the most important food-borne parasitic diseases in China. However, due to low compliance to traditional fecal examination techniques in the general population and medical personnel, ...

Hong-Mei Li, Men-Bao Qian, Yi-Chao Yang, Zhi-Hua Jiang, Kang Wei… in Parasites & Vectors (2018)

Chapter and Conference Paper

Data Fault Identification and Repair Method of Traffic Detector

The quality control and evaluation of traffic detector data are a prerequisite for subsequent applications. Considering that the PCA method is not ideal when detecting fault information with time-varying and ...

**ao-lu Li, Jia-xu Chen, **n-ming Yu, ** Zhang… in Computational Science – ICCS 2018 (2018)

Article

RETRACTED ARTICLE: Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of **ao Yao san on chronically stressed mice

**ao Yao San (XYS) is an herbal prescription which is used in the treatment of depression for thousands of years from Song dynasty in China (960–1127 A.D.), ...

**u-Fang Ding, Yue-Hua Li, Jia-Xu Chen… in BMC Complementary Medicine and Therapies (2017)

Article

Urgent needs in fostering neglected tropical diseases (NTDs) laboratory capacity in WHO Western Pacific Region: results from the external quality assessment on NTDs diagnosis in 2012–2015

Neglected tropical diseases (NTDs) are a heterogeneous group of mainly chronic, debilitating and often stigmatizing diseases that largely affects low-income and politically marginalized populations, causing a ...

Yan Lu, Glenda Gonzales, Shao-Hong Chen, Hao Li… in Infectious Diseases of Poverty (2017)