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    Article

    Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease

    Coronary artery disease (CAD) is based on the atherosclerosis of coronary artery and may manifest with myocardial infarction or angina pectoris. Although it is widely accepted that genetic factors are linked t...

    Kunihiko Hinohara, Toshiaki Nakajima, Michio Yasunami, Shigeru Houda in Human Genetics (2009)

  2. Article

    Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations

    Coronary artery disease (CAD) has become a major health problem in many countries. Recent genome-wide association studies have identified the association between rs1333049 on chromosome 9p21 and susceptibility...

    Kunihiko Hinohara, Toshiaki Nakajima, Megumi Takahashi in Journal of Human Genetics (2008)

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    Open Access

    Involvement of tumor necrosis factor receptor superfamily (TNFRSF) members in the pathogenesis of inflammatory diseases

    Current therapies for autoimmune diseases are not cures but merely palliatives, aimed at reducing symptoms. For the most part, these treatments provide nonspecific suppression of the immune system and thus do ...

    Byungsuk Kwon, Byung-Sam Kim, Hong Rae Cho in Experimental & Molecular Medicine (2003)

  4. Article

    Open Access

    Activation of monocytes, T-lymphocytes and plasma inflammatory markers in angina patients

    Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis. We analyzed the plasma levels of inflammatory markers and the degree of activation of peripheral blood m...

    Won-Ha Lee, Yoon Lee, Jong-Ran Kim, **-A Chu in Experimental & Molecular Medicine (1999)

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    Article

    Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

    Hypertrophic cardiomyopathy (HCM), the most common cause of sudden death in the young, is an autosomal dominant disease characterized by ventricular hypertrophy accompanied by myofibrillar disarrays1. Linkage stu...

    Akinori Kimura, Haruhito Harada, Jeong-Euy Park, Hirofumi Nishi in Nature Genetics (1997)