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  1. No Access

    Article

    Construction of Synthetic Microbial Consortium for Violacein Production

    Violacein, a purple-colored natural pigment produced by microbes, has anti-microbial, anti-parasitic, and anti-cancer properties. Violacein can be synthesized through a complex pathway from a carbon source via...

    Da-ae Gwon, Eui** Seo, Jeong Wook Lee in Biotechnology and Bioprocess Engineering (2023)

  2. No Access

    Article

    Genetic Biocontainment Systems for the Safe Use of Engineered Microorganisms

    Recent advances in genetic engineering and synthetic biology have enabled a variety of genetically modified microorganisms (GMOs) designed for open environmental applications. The use of GMOs in these applicat...

    Donghyeon Kim, Jeong Wook Lee in Biotechnology and Bioprocess Engineering (2020)

  3. No Access

    Article

    Cell-free biosensors for rapid detection of water contaminants

    Lack of access to safe drinking water is a global problem, and methods to reliably and easily detect contaminants could be transformative. We report the development of a cell-free in vitro transcription system...

    Jaeyoung K. Jung, Khalid K. Alam, Matthew S. Verosloff… in Nature Biotechnology (2020)

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    Chapter

    Systems Metabolic Engineering of Escherichia coli for Chemicals, Materials, Biofuels, and Pharmaceuticals

    Microorganisms are small but efficient micro-factories for producing bulk and value-added products. Systems biology and synthetic biology advanced during the last decade are enabling us to unravel the underlyi...

    Dokyun Na, ** Hwan Park, Yu-Sin Jang, Jeong Wook Lee… in Systems Metabolic Engineering (2012)

  5. No Access

    Article

    Development of sucrose-utilizing Escherichia coli K-12 strain by cloning β-fructofuranosidases and its application for l-threonine production

    Sucrose is one of the most promising carbon sources for industrial fermentation. To achieve sucrose catabolism, the sucrose utilization operons have been introduced into microorganisms that are not able to uti...

    Jeong Wook Lee, Sol Choi, ** Hwan Park… in Applied Microbiology and Biotechnology (2010)

  6. No Access

    Article

    Proteome-based physiological analysis of the metabolically engineered succinic acid producer Mannheimia succiniciproducens LPK7

    Using two-dimensional gel electrophoresis (2-DE) and mass spectrometry, the proteome of a metabolically engineered succinic acid-overproducing bacterium, Mannheimia succiniciproducens LPK7, was examined and compa...

    Jeong Wook Lee, Sang Yup Lee in Bioprocess and Biosystems Engineering (2010)

  7. No Access

    Article

    From genome sequence to integrated bioprocess for succinic acid production by Mannheimia succiniciproducens

    Mannheimia succiniciproducens is a capnophilic gram-negative bacterium isolated from bovine rumen. Wild-type M. succiniciproducens can produce succinic acid as a major fermentation product with acetic, formic, an...

    Sang Yup Lee, Ji Mahn Kim, Hyohak Song… in Applied Microbiology and Biotechnology (2008)