![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessProgramming cell-free biosensors with DNA strand displacement circuits
Cell-free biosensors are powerful platforms for monitoring human and environmental health. Here, we expand their capabilities by interfacing them with toehold-mediated strand displacement circuits, a dynamic D...
-
Protocol
ROSALIND: Rapid Detection of Chemical Contaminants with In Vitro Transcription Factor-Based Biosensors
ROSALIND (RNA Output Sensors Activated by Ligand Induction) is an in vitro biosensing system that detects small molecules using regulated transcription reactions. It consists of three key components: (1) RNA poly...
-
Article
Cell-free biosensors for rapid detection of water contaminants
Lack of access to safe drinking water is a global problem, and methods to reliably and easily detect contaminants could be transformative. We report the development of a cell-free in vitro transcription system...
-
Article
Open AccessA primer on emerging field-deployable synthetic biology tools for global water quality monitoring
Tracking progress towards Target 6.1 of the United Nations Sustainable Development Goals, “achieving universal and equitable access to safe and affordable drinking water for all”, necessitates the development ...