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Article
Fibrillary glomerulopathy in a 10-year-old female
A 10-year-old African-American female was evaluated for asymptomatic proteinuria. Initial investigation did not reveal the etiology of her renal disease. She subsequently underwent a percutaneous renal biopsy...
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Chapter
Characteristics and Mechanisms of Angiotensin II-Related Myocardial Damage
Chronic, pathophysiological elevations of angiotensin (Ang) II cause myocyte necrosis and coronary vascular damage. These adverse effects are mediated by the angiotensin II type 1 (AT1) receptor and are, therefor...
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Chapter
Myocardial Interstitial Collagen Matrix Remodeling in Response to a Chronic Elevation in Ventricular Preload or Afterload
Fibrillar collagen is an essential component of the extracellular matrix of the heart that surrounds and interconnects the coronary microcirculation, individual myocytes, groups of cardiac myofibrils, muscle f...
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Chapter
Ventricular Remodeling in Heart Failure: The Role of Myocardial Collagen
Collagen which is present in the myocardium in relatively small amounts is the most abundant structural protein of the connective tissue network. Its structural organization consists of a complex weave of coll...
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Chapter
Progressive Ventricular Dilatation in Heart Failure: The Role of Myocardial Collagenase
Fibrillar collagen is an integral component of the extracellular matrix of the heart, linking the numerous myocardial components and ensuring an efficient functioning organ. Specifically it provides for muscle...
