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Article
Relaxation of a transfer RNA specificity by removal of modified nucleotides
THE molecular recognition of specific transfer RNAs by the appropriate aminoacyl-tRNA synthetase is an important step in determining the accuracy of translation of the genetic message from nucleic acids into ...
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Chapter
Structural and Functional tRNA Mimicry of the 3’-end of Turnip Yellow Mosaic Virus RNA
The 3’-ends of several plant viral RNAs show a number of functional characteristics of tRNAs1,2; they are recognized by a set of tRNA-specific proteins, including aminoacyl-tRNA synthetases. So, the RNA of turnip...
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Article
Translational control inE. coli: The case of threonyl-tRNA synthetase
Genetic studies have shown that expression of theE. coli threonyl-tRNA synthetase (thrS) gene is negatively auto-regulated at the translational level. A region called the operator, located 110 nucleotides downstr...
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Article
Identification of an Escherichia coli S1-like protein in the spinach chloroplast ribosome
Antibodies directed against E. coli ribosomal protein S1 were used in immunoblotting assays to search for an S1-like protein in the ribosome of spinach chloroplast. An immunological cross-reaction was reproducibl...
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Chapter
Correlation Between Crystal and Solution Structures in tRNA. Yeast tRNAPhe and tRNAAsp the Models for Free and Messenger RNA Bound tRNAs
The three-dimensional structures of two elongator transfer RNAs are known in great details: first that of yeast tRNA(Phe) (1–4) and more recently that of yeast tRNA(Asp) (5–8). As seen in Figure 1, both molecu...
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Article
Influence of a Quaternary Ammonium Salt on the Infectivity of Ribonucleic Acid from Tobacco Mosaic Virus
IN a previous paper, some of us1 have shown that the quaternary ammonium salts of deoxy- and ribonucleic acids are soluble in organic solvents, and that by the addition of a concentrated solution of sodium chlori...