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    Chapter

    Neuroendocrinology of Perinatal Mental Illness

    Mental illness during pregnancy and the postpartum period is a growing health crisis. We know that at least 1 in 7 women during the perinatal period will experience a mood or anxiety disorder such as perinatal...

    Jodi Pawluski, Molly Dickens, Jamie Maguire in Neuroendocrine Regulation of Mammalian Pre… (2024)

  2. Article

    Open Access

    Gq neuromodulation of BLA parvalbumin interneurons induces burst firing and mediates fear-associated network and behavioral state transition in mice

    Patterned coordination of network activity in the basolateral amygdala (BLA) is important for fear expression. Neuromodulatory systems play an essential role in regulating changes between behavioral states, ho...

    **n Fu, Eric Teboul, Grant L. Weiss, Pantelis Antonoudiou in Nature Communications (2022)

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    Chapter

    Mechanisms of Psychiatric Comorbidities in Epilepsy

    Psychiatric illnesses, including depression and anxiety, are highly comorbid with epilepsy (for review see Josephson and Jetté (Int Rev Psychiatry 29:409–424, 2017), Salpekar and Mula (Epilepsy Behav 98:293–29...

    Jamie Maguire in Psychiatric and Behavioral Aspects of Epilepsy (2022)

  4. Article

    Open Access

    Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction

    Learned fear and safety are associated with distinct oscillatory states in the basolateral amygdala (BLA) and medial prefrontal cortex (mPFC). To determine if and how these network states support the retrieval...

    Minagi Ozawa, Patrick Davis, Jianguang Ni, Jamie Maguire in Nature Communications (2020)

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    Article

    Cellular and oscillatory substrates of fear extinction learning

    Davis et al. report that fear memories can be critically regulated by parvalbumin-expressing interneurons in the basolateral amygdala. Silencing these interneurons following fear memory extinction caused a reemer...

    Patrick Davis, Yosif Zaki, Jamie Maguire, Leon G Reijmers in Nature Neuroscience (2017)

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    Article

    The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders

    Neuroactive derivatives of steroid hormones, neurosteroids, can act on GABAA receptors (GABAARs) to potentiate the effects of GABA on these receptors. Neurosteroids become elevated to physiologically relevant lev...

    Georgina MacKenzie, Jamie Maguire in Psychopharmacology (2014)

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    Chapter

    GABAergic Control of the Hypothalamic–Pituitary–Adrenal (HPA) Axis: Role of Extrasynaptic GABAA Receptors

    The body’s physiological response to stress is mediated by the hypothalamic–pituitary–adrenal (HPA) axis, the activity of which is tightly regulated by GABAergic inhibition. Parvocellular neurosecretory neuron...

    Jamie Maguire in Extrasynaptic GABAA Receptors (2014)

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    Article

    The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

    The Rbfox family of RNA binding proteins mediate alternative splicing. Douglas Black and colleagues show that targeted deletion of the mouse Rbfox1 gene in the CNS alters splice isoforms of a subset of genes and ...

    Lauren T Gehman, Peter Stoilov, Jamie Maguire, Andrey Damianov in Nature Genetics (2011)

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    Reference Work Entry In depth

    Premenstrual Dysphoric Disorder

    Jamie Maguire, Istvan Mody in Encyclopedia of Molecular Mechanisms of Disease (2009)