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  1. No Access

    Article

    Mdm-2 binding and TAFII31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21

    Analyses of five wild-type p53 containing cell lines revealed lineage specific differences in phosphorylation of Thr18 after treatment with ionizing (IR) or ultraviolet (UV) radiation. Importantly, Thr18 phosp...

    James R Jabbur, Amy D Tabor, **aodong Cheng, Hua Wang, Motonari Uesugi… in Oncogene (2002)

  2. No Access

    Article

    DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo

    We investigated the induction and physiological role of Ser20 phosphorylation of p53 in response to DNA damage caused by ionizing radiation (IR) or ultraviolet radiation (UV). A polyclonal antibody that specif...

    James R Jabbur, Peng Huang, Wei Zhang in Oncogene (2000)

  3. Article

    Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment

    In this study, we examined the effects of radiation and ara-C on induction of apoptosis and on the apoptosis-promoting genes p53, Bax and Fas/APO-1, in BV173 human leukemia cells, which harbor the wild-type p53 g...

    Tohru Kobayashi, Sanbao Ruan, James R Jabbur, Ugo Consoli… in Cell Death & Differentiation (1998)

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