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Article
Open AccessPhase II study of necitumumab plus modified FOLFOX6 as first-line treatment in patients with locally advanced or metastatic colorectal cancer
This single-arm phase II study investigated the EGFR monoclonal antibody necitumumab plus modified FOLFOX6 (mFOLFOX6) in first-line treatment of locally advanced or metastatic colorectal cancer (mCRC).
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Article
Slepian noise approach for gaussian and Laplace moving average processes
Slepian models are derived for a stochastic process observed at level crossings of a moving average driven by a gaussian or Laplace noise. In particular, a Slepian model for the noise – the Slepian noise – is ...
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Chapter and Conference Paper
Turning Internal Product Knowledge into External Service Offers: Building PSS Capabilities
The transition from product development towards development of product-service systems (PSS) challenges manufacturing industry today. This paper is based on a case study of a company in the aerospace industry ...
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Article
Reliable X-ray diagnosis of slipped capital femoral epiphysis by combining the conventional and a new simplified geometrical method
Background: The diagnosis of subtle slipped capital femoral epiphysis (SCFE), for example in the contralateral asymptomatic hip, may require use of an exactly defined and reproducible lateral vie...
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Article
Does a single device prevent further slip** of the epiphysis in children with slipped capital femoral epiphysis?
All 170 patients (212 hips) treated between 1946 and 1992 for slipped capital femoral epiphysis (SCFE) with fixation in situ with a single device were reviewed to evaluate the incidence of further slip** of ...
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Article
External rotational positioning of the leg after intertrochanteric combined varus-derotational osteotomy in Perthes' disease
A 13-year-old boy underwent an intertrochanteric combined varus derotational osteotomy (VDO) for Perthes' disease of his right hip. After surgery he walked with his right leg externally rotated. Computed tomog...
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Chapter
Electron Transport in InGaAsP/InP Quantum Well Laser Structures
Carrier transport in quantum well (QW) lasers is one of the factors affecting the high frequency performance of these devices. Usually the transport of holes is assumed to be of major significance. However, if...
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Article
Optimal growth interrupts for very high quality InGaAs(P)/InP superlattices grown by MOVPE
The effects of different growth interrupt schemes at the compositional interfaces in 30 period InGaAs(P)/InP superlattices grown by metal-organic vapor phase epitaxy have been studied for quarternary compositi...
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Chapter
Molecular Genetics as a Tool in Clinical Transplantation
After the discovery of the HLA region in the mid 1960s and the observation that kidney grafts exchanged between HLA-identical sibs had excellent survival, national, and international graft exchange programs we...
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Chapter and Conference Paper
HLA Class II Polymorphism: Restriction Fragment Patterns Correlated to Ninth Workshop Serology and Function
Recent studies have vastly expanded our knowledge of MHC gene organization and structure [for review see 6, 7, 13]. The HLA class II gene map is presently thought to contain at least three DRβ, one DRα, two DQβ t...
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Chapter and Conference Paper
HLA-DR and DQ, Studied with Genomic Blotting, in Diabetic Families and Transplant Donor-Recipient Pairs
The DNA-DNA hybridization technique was employed to investigate the possible role of HLA class II genes other than DR in clinical kidney and bone marrow transplantation. Using cDNA probes corresponding to the ...