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  1. Article

    Open Access

    Effect of low-frequency dorsal root ganglion stimulation in the treatment of chronic pain

    The role of stimulation parameters, especially stimulation frequency is not well understood in dorsal root ganglion stimulation. Previous studies documented higher effectiveness for frequencies as low as 20 Hz...

    G. S. Piedade, S. Gillner, P. S. McPhillips, J. Vesper in Acta Neurochirurgica (2023)

  2. Article

    Open Access

    Spinal cord stimulation in non-reconstructable critical limb ischemia: a retrospective study of 71 cases

    Spinal cord stimulation (SCS) is a therapeutic option for patients with a peripheral arterial disease with critical limb ischemia (CLI) and consequent ischemic rest pain. Neuromodulation is chosen when vascula...

    G. S. Piedade, J. Vesper, D. Reichstein, A. K. Dauphin, S. Damirchi in Acta Neurochirurgica (2023)

  3. Article

    Open Access

    Frequency dependency of therapeutic efficacy in dorsal root ganglion stimulation for neuropathic pain

    The influence of the stimulation frequency on the outcomes of dorsal root ganglion stimulation (DRG-S) to treat pain is not well understood. It is assumed that specific neural components dedicated to different...

    G. S. Piedade, S. Gillner, P. S. McPhillips, J. Vesper in Acta Neurochirurgica (2022)

  4. Article

    Open Access

    Surgical management of “Twiddler syndrome” in patients with deep brain stimulation: a technical note and review of the literature

    The Twiddler syndrome (TS) describes a situation in which the implanted impulse generator (IPG) rotates several times around its own axis in the subcutaneous pocket. This can lead to severe mechanical damage o...

    Z. Krause Molle, P. Slotty, J. Vesper in Acta Neurochirurgica (2022)

  5. Article

    Open Access

    The role of periradicular infiltration in dorsal root ganglion stimulation for chronic neuropathic pain

    Targeting the correct spinal level is essential in dorsal root ganglion (DRG) stimulation. Anatomical selection of the DRG alone is not ideal since the pain area is not necessarily confined to the borders of t...

    H. Sievert, G. S. Piedade, P. McPhillips, J. Vesper, P. J. Slotty in Acta Neurochirurgica (2021)

  6. No Access

    Article

    Synergetic efficacy of simultaneous DRG- and traditional spinal cord stimulation

    Dorsal root ganglion stimulation has established its role in chronic pain states and is commonly used as an alternative treatment to traditional spinal cord stimulation. Due to its approach, DRG stimulation is...

    G. S. Piedade, J. Vesper, Philipp J. Slotty in Acta Neurochirurgica (2020)

  7. No Access

    Article

    The surgical technique of occipital nerve stimulation

    Occipital nerve stimulation is increasingly used in the treatment of primary headache disorders. We describe a surgical technique applying preoperative fluoroscopy and intraoperative tactile orientation design...

    P. J. Slotty, G. Bara, J. Vesper in Acta Neurochirurgica (2015)

  8. No Access

    Article

    The impact of brain shift in deep brain stimulation surgery: observation and obviation

    The impact of brain shift on deep brain stimulation surgery is considerable. In DBS surgery, brain shift is mainly caused by CSF loss. CSF loss can be estimated by post-surgical intracranial air. Different app...

    P. J. Slotty, M. A. Kamp, C. Wille, T. M. Kinfe, H. J. Steiger in Acta Neurochirurgica (2012)

  9. Article

    Open Access

    Retrospective analysis of treatment outcome in 315 patients with oligodendroglial brain tumors

    Although chemotherapy with procarbazine, lomustine and vincristine (PCV) is considered to be well tolerated, side effects frequently lead to dose reduction or even discontinuation of treatment of oligodendrogl...

    J Vesper, E Graf, C Wille, J Tilgner, M Trippel, G Nikkhah, CB Ostertag in BMC Neurology (2009)

  10. No Access

    Article

    Neurochirurgische Standards bei tiefer Hirnstimulation

    Voraussetzung für die therapeutische Anwendung der tiefen Hirnstimulation (THS) ist eine stereotaktisch-neurochirurgische Operation mit Implantation von Hirnelektroden in subkortikale Zielstrukturen des Gehirn...

    Prof. Dr. J. Voges, K. Kiening, J.K. Krauss, G. Nikkhah, J. Vesper in Der Nervenarzt (2009)

  11. No Access

    Chapter

    Systeme zur tiefen Hirnstimulation

    In den späten 1960er Jahren wurden erstmals Elektroden entwickelt, die eine kontinuierliche Stimulation neuraler Strukturen erlaubten [16, 17, 30, 32, 36]. Zunächst wurden diese halbimplantierbaren Radiofrequenzs...

    J. Vesper, A. Sarem-Aslani, D. Hellwig in Tiefe Hirnstimulation (2004)

  12. No Access

    Chapter

    Intraoperative neurophysiologische Untersuchung: MakroStimulation und evozierte Potenziale

    Intraoperative klinische neurophysiologische Untersuchungen sind integrale Komponenten funktioneller stereotaktischer Eingriffe und beinhalten die Markostimulation, die Mikroelek- trodenableitung, sowie die Ab...

    J. Volkmann, J. Vesper, J. K. Krauss in Tiefe Hirnstimulation (2004)

  13. No Access

    Chapter and Conference Paper

    Deep Brain Stimulation of the Globus Pallidus Internus (GPI) for Torsion Dystonia — A Report of two Cases

    Generalized dystonia is known as a type of movement disorder in which pharmacotherapeutic options are very limited. Deep Brain Stimulation (DBS) is well established for Parkinson’s disease (PD) and tremor domi...

    J. Vesper, F. Klostermann, Th. Funk in Functional Rehabilitation in Neurosurgery … (2002)

  14. No Access

    Article

    Permanent Postoperative Anosmia: A Serious Complication of Neurovascular Decompression in the Sitting Position

    J. Ramsbacher, J. Vesper, M. Brock in Acta Neurochirurgica (2000)

  15. No Access

    Article

    Periradicular therapy in lumbar radicular syndromes: Methodology and results

    Periradicular therapy (PRT) has become popular in the treatment of lumbar radicular complaints, both primary, due to disc herniations (Group 1), and postoperative, following disc surgery (Group 2). However, hi...

    M. Lutze M. D., R. Stendel, J. Vesper, M. Brock in Acta Neurochirurgica (1997)