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Article
Loop-Mediated Isothermal Amplification as a Promising Method for Mass COVID-19 Diagnostics
Real-time reverse-transcription polymerase chain reaction (RT-PCR) is currently the most popular method for early COVID-19 diagnostics. However, loop-mediated isothermal amplification (LAMP) is superior to rea...
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Article
In Vitro System for the Detection of Prostate Cancer Markers via Loop-Mediated Isothermal Amplification
Loop-mediated isothermal amplification (LAMP) of nucleic acids enables the detection of amplification products 10–20 min after the beginning of the reaction. An intraoperative method for the detection of metas...
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Article
Epithelial to Mesenchymal Transition Marker in 2D and 3D Colon Cancer Cell Cultures in the Presence of Laminin 332 and 411
The loss of apical-basal cell polarity is a necessary stage of the epithelial-mesenchymal transition (EMT). Polarized epithelial cells interact with the basement membrane (BM) and, in particular, with laminins...
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Article
Circulating microRNAs
The detection of miRNAs in plasma and other body fluids opened up a fascinating possibility that animal noncoding RNAs can act as extracellular signaling molecules. In this review, we discuss recent progress i...
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Article
New functions of small nucleolar RNAs
Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also inv...
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Article
Small nucleolar RNAs and their genes in vertebrates
Genes of box C/D small nucleolar RNAs (snoRNAs) were searched for in the genomes of members of all classes of vertebrates that do not belong to placental mammals. A tendency for an increase in the number of co...
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Article
Noncoding RNAs
There has been substantial progress in studies on non-protein-coding RNAs (ncRNAs) during the last decade. Due to the development of new experimental approaches, a wide variety of such molecules have been foun...
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Article
Small nucleolar RNA
The review considers small nucleolar RNAs (snoRNAs), an abundant group of non-protein-coding RNAs. In association with proteins, snoRNAs determine the two most common nucleotide modifications in rRNA and some ...
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Article
Small nucleolar RNA genes
Small nucleolar RNAs (snoRNAs) are one of the most numerous and well-studied groups of non-protein-coding RNAs. In complex with proteins, snoRNAs perform the two most common nucleotide modifications in rRNA: 2...
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Article
Mammalian U87 Small Nucleolar RNA and Its Host Gene
Most small nucleolar RNAs (snoRNAs) of the C/D box family determine the site of ribose methylation in rRNA. A new snoRNA, U87, was found in mammals, assigned to the C/D box family, and assumed to play a role i...