Skip to main content

5 Result(s)

within I. M. Tsypina Remove this filter

and

  1. No Access

    Article

    Laminin 521 Modulates the Сytotoxic Effect of 5-Fluorouracil on HT29 Colorectal Cancer Cells

    The cytotoxic effect of 5-fluorouracil (5FU) and regorafenib (RF), drugs with different mechanisms of action used to treat colorectal cancer, on an HT29 cell line cultured on plastic or laminin 521 (LM-521) ha...

    M. P. Raigorodskaya, A. Turchinovich… in Applied Biochemistry and Microbiology (2020)

  2. No Access

    Article

    Epithelial to Mesenchymal Transition Marker in 2D and 3D Colon Cancer Cell Cultures in the Presence of Laminin 332 and 411

    The loss of apical-basal cell polarity is a necessary stage of the epithelial-mesenchymal transition (EMT). Polarized epithelial cells interact with the basement membrane (BM) and, in particular, with laminins...

    D. V. Maltseva, J. A. Makarova, A. Yu. Khristichenko, I. M. Tsypina… in Molecular Biology (2019)

  3. No Access

    Article

    Metabolic Reprogramming of Trophoblast Cells in Response to Hypoxia

    Hypoxia of trophoblast cells is an important regulator of normal development of the placenta. However, some pathological states associated with hypoxia, e.g. preeclampsia, impair the functions of placental cells....

    E. N. Knyazev, G. S. Zakharova… in Bulletin of Experimental Biology and Medic… (2019)

  4. No Access

    Article

    Oxyquinoline-Dependent Changes in Claudin-Encoding Genes Contribute to Impairment of the Barrier Function of the Trophoblast Monolayer

    Natural response to hypoxia critically depends on rapid stabilization of hypoxia-inducible factor (HIF). Under normoxic conditions, HIF-prolyl hydroxylases mark α-subunits of HIF for degradation, while hypoxia...

    E. N. Knyazev, V. A. Petrov, I. N. Gazizov… in Bulletin of Experimental Biology and Medic… (2019)

  5. No Access

    Article

    Regularities of recent slope processes in the USSR

    The paper presents the regularities of the development of recent slope processes in the U.S.S.R. caused by natural factors, the most important of which are the relief, lithologic-petrographic composition of ro...

    M. V. Churinov, I. M. Tsypina… in Bulletin of the International Association … (1978)