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Article
Open AccessBenign urinary bladder masses: rare entities
This study aimed to present the characteristics and outcomes of benign urinary bladder masses, as well as the characteristics of the patients diagnosed with such lesions.
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Article
Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity
Defects in pathways governing genomic fidelity have been linked to improved response to immune checkpoint blockade therapy (ICB). Pathogenic POLE/POLD1 mutations can cause hypermutation, yet how diverse mutations...
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Article
CTCF mediates dosage- and sequence-context-dependent transcriptional insulation by forming local chromatin domains
Insulators play a critical role in spatiotemporal gene regulation in animals. The evolutionarily conserved CCCTC-binding factor (CTCF) is required for insulator function in mammals, but not all of its binding ...
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Protocol
Proximity Ligation-Assisted ChIP-Seq (PLAC-Seq)
Proximity ligation-assisted ChIP-Seq (PLAC-Seq), also known as HiChIP, is a method to detect and quantify chromatin contacts anchored at genomic regions bound by specific proteins or histone modifications. By ...
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Article
Cell-type-specific 3D epigenomes in the develo** human cortex
Lineage-specific epigenomic changes during human corticogenesis have been difficult to study owing to challenges with sample availability and tissue heterogeneity. For example, previous studies using single-ce...
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Article
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome
Simultaneous profiling of transcriptome and chromatin accessibility within single cells is a powerful approach to dissect gene regulatory programs in complex tissues. However, current tools are limited by mode...
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Article
Publisher Correction: Sensory experience remodels genome architecture in neural circuit to drive motor learning
In this Letter, ‘≥’ should be ‘≤’ in the sentence: “Intra-chromosomal reads were further split into short-range reads (≥1 kb) and long-range reads (>1 kb)”. This error has been corrected online.
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Article
Sensory experience remodels genome architecture in neural circuit to drive motor learning
Neuronal-activity-dependent transcription couples sensory experience to adaptive responses of the brain including learning and memory. Mechanisms of activity-dependent gene expression including alterations of ...
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Article
Influence of Shielding Gas Composition on Structure and Mechanical Properties of Wire and Arc Additive Manufactured Inconel 625
Wire and arc additive manufacturing (WAAM) is becoming an increasingly important process for manufacture of components with complex geometry, being used for products made for products made from expensive metal...
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Article
Molecular markers for Diadegma (Hymenoptera: Ichneumonidae) species distinction and their use to study the effects of companion plants on biocontrol of the diamondback moth
Molecular markers facilitate the quantification of parasitization of pest species and the distinction of related parasitoid species. We designed new markers that allow the distinction of often misidentified Diade...
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Article
Tradeoffs, competition, and coexistence in eastern deciduous forest ant communities
Ecologists have long sought to explain the coexistence of multiple potentially competing species in local assemblages. This is especially challenging in species-rich assemblages in which interspecific competit...
