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Open AccessCis-regulatory evolution of the recently expanded Ly49 gene family
Comparative genomics has revealed the rapid expansion of multiple gene families involved in immunity. Members within each gene family often evolved distinct roles in immunity. However, less is known about the ...
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Article
Open AccessUropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome
Previous urinary tract infections (UTIs) can predispose one to future infections; however, the underlying mechanisms affecting recurrence are poorly understood. We previously found that UTIs in mice cause diff...
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Article
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements
Cryptic promoters within transposable elements (TEs) can be transcriptionally reactivated in tumors to create new TE-chimeric transcripts, which can produce immunogenic antigens. We performed a comprehensive s...
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Cell-type-specific 3D epigenomes in the develo** human cortex
Lineage-specific epigenomic changes during human corticogenesis have been difficult to study owing to challenges with sample availability and tissue heterogeneity. For example, previous studies using single-ce...
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Article
Author Correction: Exploring the coronavirus pandemic with the WashU Virus Genome Browser
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Exploring the coronavirus pandemic with the WashU Virus Genome Browser
The WashU Virus Genome Browser is a web-based portal for efficient visualization of viral ‘omics’ data in the context of a variety of annotation tracks and host infection responses. The browser features both a...
