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  1. Article

    Open Access

    The molecular mechanisms underlying the ERα-36-mediated signaling in breast cancer

    Alterations in estrogen-mediated cellular signaling have largely been implicated in the pathogenesis of breast cancer. Here, we investigated the signaling regulation of a splice variant of the estrogen recepto...

    S Omarjee, J Jacquemetton, C Poulard, N Rochel, A Dejaegere, Y Chebaro… in Oncogene (2017)

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  2. Article

    Open Access

    Phase II study of the PI3K inhibitor BKM120 in patients with advanced or recurrent endometrial carcinoma: a stratified type I–type II study from the GINECO group

    Patients with metastatic endometrial carcinoma have a poor prognosis and PIK3CA mutations and amplifications are common in these cancers. This study evaluated the efficacy and safety of the pure PI3K inhibitor...

    P-E Heudel, M Fabbro, C Roemer-Becuwe, M C Kaminsky, A Arnaud… in British Journal of Cancer (2017)

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  3. Article

    Open Access

    Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis

    Cellular senescence, a stable proliferation arrest, is induced in response to various stresses. Oncogenic stress-induced senescence (OIS) results in blocked proliferation and constitutes a fail-safe program co...

    C Wiel, A Augert, D F Vincent, D Gitenay, D Vindrieux, B Le Calvé… in Cell Death & Disease (2013)

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  4. No Access

    Chapter and Conference Paper

    Hyperplasie canalaire atypique sur biopsies à l’aiguille : améliorer le diagnostic histologique

    Trois à 12 % des diagnostics effectués sur biopsies percutanées correspondent à des « lésions frontières » du groupe B3 de la classification proposée par le programme de dépistage des cancers du sein au Royaum...

    M. -E. Fondrevelle, N. Guerin, M. Peix… in Cancer du sein : surdiagnostic, surtraitem… (2012)

  5. No Access

    Chapter

    Thérapeutiques du cancer de l’ovaire

    Le but du traitement chirurgical du cancer épithélial de l’ovaire est de réaliser une stadification anatomique précise et une réduction tumorale optimale.

    P. Heudel, I. Ray-Coquard, P. Méeus, I. Treilleux, I. Labidi… in Thérapeutique du cancer (2011)

  6. No Access

    Chapter

    Ovaire

    Les tumeurs germinales malignes représentent 3 % des tumeurs de l’ovaire. Leur incidence annuelle en France est de 0,5 pour 100 000 femmes et l’on peut estimer le nombre de nouveaux cas en France...

    I. Ray-Coquard, J.-P. Guastalla, I. Treilleux in Tumeurs malignes rares (2010)

  7. Article

    Open Access

    Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype

    Dicer, a ribonuclease, is the key enzyme required for the biogenesis of microRNAs and small interfering RNAs and is essential for both mammalian development and cell differentiation. Recent evidence indicates ...

    G Grelier, N Voirin, A-S Ay, D G Cox, S Chabaud, I Treilleux… in British Journal of Cancer (2009)

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  8. No Access

    Article

    Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles

    Invasive ductal carcinomas (IDCs) and invasive lobular carcinomas (ILCs) are the two major pathological types of breast cancer. Epidemiological and histoclinical data suggest biological differences, but little...

    F Bertucci, B Orsetti, V Nègre, P Finetti, C Rougé, J-C Ahomadegbe, F Bibeau… in Oncogene (2008)

  9. No Access

    Chapter

    Les différents types histologiques des cancers ovariens

    I. Treilleux in Les cancers ovariens (2006)

  10. No Access

    Chapter

    Traitement des tumeurs rares de l’ovaire. Expérience de l’observatoire francophone des tumeurs malignes rares de l’ovaire

    I. Ray-Coquard, P. Binon, J.-Y. Blay, H. Curé, A. Fléchon… in Les cancers ovariens (2006)

  11. No Access

    Article

    Tumeurs rares malignes de l’ovaire

    Les tumeurs rares de la sphère ovarienne adulte représentent moins de 10 % des tumeurs ovariennes de l’adulte. Le traitement des tumeurs rares de l’ovaire est actuellement établi comme suit:

    I. Ray-Coquard, J.-P. Guastalla, I. Treilleux, P. Biron, J.-Y. Blay, H. Curé… in Oncologie (2005)

  12. Article

    Open Access

    Agreement between chromogenic in situ hybridisation (CISH) and FISH in the determination of HER2 status in breast cancer

    Determination of the HER2/neu (HER2) status in breast carcinoma has become necessary for the selection of breast cancer patients for trastuzumab therapy. Amplification of the gene analysed by fluorescence in situ

    L Arnould, Y Denoux, G MacGrogan, F Penault-Llorca, M Fiche… in British Journal of Cancer (2003)

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