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  1. No Access

    Article

    Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape

    Oncogenic-stress-induced senescence (OIS) is a stress response allowing normal cells, when receiving oncogenic signals, to stably arrest their proliferation. OIS thus acts to prevent aberrant cell proliferatio...

    C Wiel, B Gras, D Vindrieux, M Warnier, D Gitenay, B Le Calvé, M Ferrand… in Oncogene (2016)

  2. Article

    Erratum: Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

    Correction to: Cell Death and Disease (2014) 5, e1089; doi:10.1038/cddis.2014.63; published online 27 February 2014 Since the publication of this paper the authors have noticed an error in the abstract section...

    D Gitenay, C Wiel, H Lallet-Daher, D Vindrieux, S Aubert, L Payen… in Cell Death & Disease (2014)

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  3. Article

    Open Access

    Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

    Oncogenic stress-induced senescence (OIS) prevents the ability of oncogenic signals to induce tumorigenesis. It is now largely admitted that the mitogenic effect of oncogenes requires metabolic adaptations to ...

    D Gitenay, C Wiel, H Lallet-Daher, D Vindrieux, S Aubert, L Payen… in Cell Death & Disease (2014)

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  4. Article

    Open Access

    Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis

    Cellular senescence, a stable proliferation arrest, is induced in response to various stresses. Oncogenic stress-induced senescence (OIS) results in blocked proliferation and constitutes a fail-safe program co...

    C Wiel, A Augert, D F Vincent, D Gitenay, D Vindrieux, B Le Calvé… in Cell Death & Disease (2013)

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  5. No Access

    Article

    Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells

    Early growth response-1 (Egr-1) is overexpressed in human prostate tumors and contributes to cancer progression. On the other hand, mutation of p53 is associated with advanced prostate cancer, as well as with ...

    L Sauer, D Gitenay, C Vo, V T Baron in Oncogene (2010)

  6. No Access

    Article

    Fruits et cancer: de la cancérogenèse à l’épidémiologie

    Si l’origine génétique des cancers est reconnue, il est de plus en plus admis que les facteurs environnementaux soient prédominants. Les produits végétaux sont considérés comme protecteurs. Les études épidémio...

    J. Talvas, D. Gitenay, E. Rock in Phytothérapie (2008)