-
Article
Open AccessA refined molecular taxonomy of breast cancer
The current histoclinical breast cancer classification is simple but imprecise. Several molecular classifications of breast cancers based on expression profiling have been proposed as alternatives. However, th...
-
Article
Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles
Invasive ductal carcinomas (IDCs) and invasive lobular carcinomas (ILCs) are the two major pathological types of breast cancer. Epidemiological and histoclinical data suggest biological differences, but little...
-
Article
Open AccessGenetic profiling of chromosome 1 in breast cancer: map** of regions of gains and losses and identification of candidate genes on 1q
Chromosome 1 is involved in quantitative anomalies in 50–60% of breast tumours. However, the structure of these anomalies and the identity of the affected genes remain to be determined. To characterise these a...
-
Article
Open AccessMolecular cytogenetic analysis of breast cancer cell lines
The extensive chromosome rearrangements of breast carcinomas must contribute to tumour development, but have been largely intractable to classical cytogenetic banding. We report here the analysis by 24-colour ...
