19 Result(s)

Article

Use of totally implantable catheters for peripheral blood stem cell apheresis

Collection of PBSC by leukapheresis requires one venous access (VA) for inflow and one for outflow. The use of implantable venous access devices (IVAD) has never been reported in this setting. We retrospective...

L Carausu, G Clapisson, I Philip, H Sebban, P Marec-Bérard in Bone Marrow Transplantation (2007)

Article

Is there a correlation between age and D-aspartic acid in human knee cartilage?

L-Aspartic acid (L-Asp) is one of the fastest racemizing amino acids such that the abnormal D-form (D-Asp) has been found in stable biological human tissues such as dentin in teeth, eye lens and ...

G. Fisher, S. Lopez, K. Peterson, T. Goff, I. Philip, R. Gaviria, N. Lorenzo… in Amino Acids (2007)

Article

Congenital bowel perforation in twin-to-twin transfusion syndrome

Two unrelated survivors of twin-to-twin transfusion syndrome (TTTS) presented with intestinal perforation at birth. Both were localised perforations without any suggestion of widespread ischaemic disease to th...

I. Philip, W. Ford, R. Haslam in Pediatric Surgery International (2002)

Article

Autologous transplantation in acute myeloid leukemia: peripheral blood stem cell harvest after mobilization in steady state by granulocyte colony-stimulating factor alone

In order to determine whether granulocyte colony-stimulating factor (G-CSF) alone initiated during steady state was able to mobilize peripheral blood stem cells (PBSC) in acute myeloid leukemia (AML) and to a...

E. Voog, Q. Le, I. Philip, B. Benetaib, M. Michallet, D. Fiere… in Annals of Hematology (2001)

Article

Late autologous transplantation in chronic myelogenous leukemia with peripheral blood progenitor cells mobilized by G-CSF and interferon-α

In chronic myelogenous leukemia (CML), autologous stem cell transplantation could be a promising new approach for patients with no cytogenetic response after interferon α (IFN-α) therapy. We report data on 28 ...

M Michallet, A Thiébaut, I Philip, C Charrin, C Vigouroux, X Thomas, K Bilger… in Leukemia (2000)

Article

Research controversies in management of oral mucositis

 The management of mucositis is the subject of many controversies, and the optimal treatment is still not known. Several evaluation scoring systems have been described, but no one of these is appropriate to al...

P. Biron, C. Sebban, R. Gourmet, G. Chvetzoff, I. Philip… in Supportive Care in Cancer (2000)

Article

Immunological and molecular detection of tumor contamination in leukapheresis products from children with disseminated neuroblastoma: implication for evaluation of tumor cell depletion after CD34 selection

A Tchirkov, J Kanold, V Combaret, I Philip, F Kwiatkowski… in Bone Marrow Transplantation (1999)

Article

High-dose chemotherapy with hematopoietic stem cell transplantation in patients with mantle cell or diffuse centrocytic non-Hodgkin’s lymphomas: a single center experience on 18 patients

Between 1985 and 1996, 18 patients with diffuse centrocytic lymphoma (DCL), including nine patients with an established histological and phenotypic diagnosis of mantle cell lymphoma (MCL), received 19 courses ...

J-Y Blay, C Sebban, C Surbiguet, M Ouachée, I Philip… in Bone Marrow Transplantation (1998)

Chapter

Peripheral Blood Stem Cells Mobilization with G-CSF (FILGRASTIM) Alone for Autologous Transplant in Myeloid and Lymphoid Malignancies

In order to determine whether granulocyte colony-stimulating factor (G-CSF) alone was capable of mobilizing peripheral blood stem cells (PBSC) in myeloid as well in lymphoid malignancies, G-CSF (filgrastim), 5...

Eric Archimbaud M.D, M. Michallet, I. Philip… in Molecular Biology of Hematopoiesis 5 (1996)

Article

Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study

In the LMCE1 study using a single course of megatherapy most of the relapses occurred during the first 2 years after autologous bone marrow transplantation. A second pilot study (LMCE2) was therefore set up us...

T Philip, R Ladenstein, JM Zucker, R Pinkerton, E Bouffet… in British Journal of Cancer (1993)

Chapter and Conference Paper

Interleukin-2 (IL-2) After Autologous Bone Marrow Transplantation (BMT):A Pilot Study of Late Administration, 2–3 Months Post ABMT

Association of high-dose radiotherapy ± chemotherapy can cure poor risk hematological neoplasias and solid tumors. This cure is related to the treatment dose effect as well as to the immunological effect (graf...

D. Maraninchi, D. Blaise, D. Olive, M. Attal… in Cytokines in Hemopoiesis, Oncology, and AI… (1990)

Chapter and Conference Paper

rIL-2 Immunotherapy for 19 Children with Advanced Metastatic Neuroblastoma

Considerable progress has been achieved in the treatment of stage IV neuroblastoma in children over 1 year of age. Induction therapy and surgery followed by vincristine, high-dose melphalan, total body irridia...

M. C. Favrot, J. Michon, E. Bouffet… in Cytokines in Hemopoiesis, Oncology, and AI… (1990)

Chapter and Conference Paper

Adoptive Immunotherapy with IL-2 in 27 Patients with Metastatic Renal Cell Carcinoma

Adoptive immunotherapy with IL-2 and LAK cells induces tumor regressions in humans as well as in animals [1, 2]. Previous reports [3–5] clearly demonstrated the efficiency of in vivo IL-2 in melanoma and renal...

S. Négrier, T. Philip, A. Mercatello… in Cytokines in Hemopoiesis, Oncology, and AI… (1990)

Article

Immunological detection of neuroblastoma cells in bone marrow harvested for autologous transplantation

In about 50% of patients with stage IV neuroblastoma, micrometastases are present in the bone marrow when it is harvested for an autograft to follow induction therapy, and the risk of graft contamination by ne...

V Combaret, MC Favrot, B Kremens, I Philip, C Bailly… in British Journal of Cancer (1989)

Article

Histological, cytological and immunological analyses are complementary for the detection of neuroblastoma cells in bone marrow

On 80 occasions 4 iliac biopsy trephines and 4 iliac aspirations were performed in 37 children with neuroblastoma at various stages of the disease. In 38 of these procedures, tumour cells were detected. In 24%...

M C Favrot, D Frappaz, O Maritaz, I Philip, B Fontaniere… in British Journal of Cancer (1987)