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  1. No Access

    Article

    Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway

    Pathological angiogenesis (PA) contributes to various ocular diseases, including age-related macular degeneration, diabetic retinopathy, and retinopathy of prematurity, which are major causes of blindness over...

    Yi-Hsun Huang, Cheng-Hsiang Kuo, I-Chen Peng… in Cellular and Molecular Life Sciences (2021)

  2. Article

    Open Access

    Pathophysiological implications of hypoxia in human diseases

    Oxygen is essentially required by most eukaryotic organisms as a scavenger to remove harmful electron and hydrogen ions or as a critical substrate to ensure the proper execution of enzymatic reactions. All nuc...

    Pai-Sheng Chen, Wen-Tai Chiu, Pei-Ling Hsu, Shih-Chieh Lin… in Journal of Biomedical Science (2020)

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