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Article
Open AccessRejuvenating aged microglia by p16ink4a-siRNA-loaded nanoparticles increases amyloid-β clearance in animal models of Alzheimer’s disease
Age-dependent accumulation of amyloid plaques in patients with sporadic Alzheimer’s disease (AD) is associated with reduced amyloid clearance. Older microglia have a reduced ability to phagocytose amyloid, so ...
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Article
Open AccessSurface chemistry of graphitic carbon nitride: do** and plasmonic effect, and photocatalytic applications
To achieve the United Nations' Sustainable Development Goal (SDG7) of limiting global temperature rise to less than 1.5 °C, it is crucial to reduce non-renewable energy sources and curb the production of green...
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Article
Protective Effects of ShcA Protein Silencing for Photothrombotic Cerebral Infarction
Reactive oxygen species (ROS) exacerbate stroke-induced cell damage. We found that ShcA, a protein that regulates ROS, is highly expressed in a Rose Bengal photothrombosis model. We investigated whether ShcA i...
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Article
Open AccessTAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model
Because inflammation in osteoarthritis (OA) is related to the Toll-like receptor 4 (TLR4) signaling cascades, TLR4 is a reasonable target for develo** therapeutics for OA. Thus, we investigated whether TAP2,...
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Article
Open AccessPsychological characteristics and associations between living kidney transplantation recipients and biologically related or unrelated donors
Although recipients and donors in living kidney transplantation experience psychological distress—including depression and anxiety—during the pre-operative period, very few studies have evaluated the related p...
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Article
Association Between Carotid Ultrasonography Findings and Colorectal Adenoma in Asymptomatic Adults
Coexistence of colorectal neoplasia and atherosclerotic cardiovascular disease has been reported. Subclinical atherosclerosis can be evaluated noninvasively and easily by assessing carotid intima–media thickne...
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North Korean Defectors and Human Resource Development in South Korea
This chapter aims to examine how human resource development (HRD) functions for North Korean defectors (NKDs) in South Korean society using an integrative literature review. While we analyze existing studies a...
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Article
The Academic Credit Bank System in the Republic of Korea: An effective medium for lifelong learning in higher education?
Drawing on critical theory for adult education, the authors of this article examine the Academic Credit Bank System (ACBS), an open educational system operating in the Republic of Korea since 1998. It was desi...
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Article
Open AccessLoss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish
The Ewing sarcoma family of tumors expresses aberrant EWSR1- (EWS) fusion genes that are derived from chromosomal translocation. Although these fusion genes are well characterized as transcription factors, their ...
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Article
Open AccessReceptor activator of NF-κB ligand enhances the activity of macrophages as antigen presenting cells
Receptor activator of NFκB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,...
