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    Article

    Cloning, construction of prokaryotic expression vector and expression ofEscherichia coli cytosine deaminase gene

    Cytosine deaminase gene ofEscherichia coli strain H-30 was cloned, and its initiation codon of ‘GTG’ was mutated to ‘ATG’ by PCR. Prokaryotic recombinant expression vector pBV220-CD was constructed. Clone with hi...

    Shengjun Ren, Huiqiu Jiang, Jianren Gu in Chinese Science Bulletin (1998)

  2. Article

    The inhibitory effect of transthyretin gene on growth of human hepatoma cells

    Transthyretin(TTR) gene was highly expressed in normal liver and it has been found to be deleted in part of DNA samples from human hepatic cancer. Its mRNA expression was suppressed in most hepatoma samples. I...

    Chaoting Liu, ** Yao, Daizong Li, Huiqiu Jiang, Jianren Gu in Cell Research (1994)

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    Article

    Simultaneous over-expression of insulin-like growth factor-II (IGF II) and IGF-II receptor (IGF-II R) genes in human primary cancer-implication of autocrine and paracrine mechanism in autonomous growth of hepatic cancer

    This is first report about the simultaneous over-expression of both Insulin-like growth factor (IGF-II) and its receptor (IGF-II R) at mRNA level in human primary hepatic Cancer (PHC). In 10 PHC samples from C...

    **aomei Zhou, Jianren Gu, Yuanqing Cheng in Chinese Journal of Cancer Research (1992)