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Article
Open AccessText mining and portal development for gene-specific publications on Alzheimer’s disease and other neurodegenerative diseases
Tremendous research efforts have been made in the Alzheimer’s disease (AD) field to understand the disease etiology, progression and discover treatments for AD. Many mechanistic hypotheses, therapeutic targets...
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Article
Open AccessDigital twins for health: a sco** review
The use of digital twins (DTs) has proliferated across various fields and industries, with a recent surge in the healthcare sector. The concept of digital twin for health (DT4H) holds great promise to revoluti...
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Article
Open AccessPITPNC1 Suppress CD8+ T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155
Radioresistance is a primary factor contributing to the failure of rectal cancer treatment. Immune suppression plays a significant role in the development of radioresistance. We have investigated the potential...
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Article
Open AccessMycobacterium tuberculosis co-infection is associated with increased surrogate marker of the HIV reservoir
Tuberculosis (Tb) is the most frequent opportunistic infection among people living with HIV infection. The impact of Tb co-infection in the establishment and maintenance of the HIV reservoir is unclear.
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Article
Open AccessTranscription factor expression as a predictor of colon cancer prognosis: a machine learning practice
Colon cancer is one of the leading causes of cancer deaths in the USA and around the world. Molecular level characters, such as gene expression levels and mutations, may provide profound information for precis...
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Article
Open AccessHighly robust model of transcription regulator activity predicts breast cancer overall survival
While several multigene signatures are available for predicting breast cancer prognosis, particularly in early stage disease, effective molecular indicators are needed, especially for triple-negative carcinoma...
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Article
Open AccessA patient-oriented clinical decision support system for CRC risk assessment and preventative care
Colorectal Cancer (CRC) is the third leading cause of cancer death among men and women in the United States. Research has shown that the risk of CRC associates with genetic and lifestyle factors. It is possibl...
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Article
Open AccessDual-gated volumetric modulated arc therapy
Gated Volumetric Modulated Arc Therapy (VMAT) is an emerging radiation therapy modality for treatment of tumors affected by respiratory motion. However, gating significantly prolongs the treatment time, as del...
