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  1. Article

    Open Access

    Digital twins for health: a sco** review

    The use of digital twins (DTs) has proliferated across various fields and industries, with a recent surge in the healthcare sector. The concept of digital twin for health (DT4H) holds great promise to revoluti...

    Evangelia Katsoulakis, Qi Wang, Huanmei Wu, Leili Shahriyari in npj Digital Medicine (2024)

  2. No Access

    Article

    A Review of Stochastic and Deterministic Modeling of Stem Cell Dynamics

    This paper briefly describes recent mathematical models that use stochastic and deterministic approaches to understand stem cell dynamics and how these models are utilized to study the roles of stem cells’ dyn...

    Shaojun Gong, Leili Shahriyari in Current Stem Cell Reports (2023)

  3. Article

    Open Access

    Immune classification of clear cell renal cell carcinoma

    Since the outcome of treatments, particularly immunotherapeutic interventions, depends on the tumor immune micro-environment (TIM), several experimental and computational tools such as flow cytometry, immunohi...

    Sumeyye Su, Shaya Akbarinejad, Leili Shahriyari in Scientific Reports (2021)

  4. No Access

    Article

    Modeling Cell Dynamics in Colon and Intestinal Crypts: The Significance of Central Stem Cells in Tumorigenesis

    Colon and intestinal crypts have been widely chosen to study cell dynamics because of their fairly simple structures. In the colon and intestinal crypts, stem cells (SCs) are located at very bottom of the cryp...

    Ali Mahdipour-Shirayeh, Leili Shahriyari in Bulletin of Mathematical Biology (2018)

  5. No Access

    Chapter

    Fluid Dynamics of Nematocyst Prey Capture

    A nematocyst is a specialized organelle within cells of jellyfish and other Cnidarians that sting. Nematocysts are also present in some single-celled protists. They contain a barbed, venomous thread that accel...

    Wanda Strychalski, Sarah Bryant in Understanding Complex Biological Systems w… (2018)

  6. Article

    Open Access

    The role of cell location and spatial gradients in the evolutionary dynamics of colon and intestinal crypts

    Colon and intestinal crypts serve as an important model system for adult stem cell proliferation and differentiation. We develop a spatial stochastic model to study the rate of somatic evolution in a normal cr...

    Leili Shahriyari, Natalia L. Komarova, Alexandra Jilkine in Biology Direct (2016)

  7. No Access

    Article

    Translating graphs by mean curvature flow

    The aim of this work is studying translating graphs by mean curvature flow in \(\mathbb {R}^3\) ...

    Leili Shahriyari in Geometriae Dedicata (2015)