7,339 Result(s)
-
Article
Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis
Septic cardiomyopathy is a severe cardiovascular disease with a poor prognosis. Previous studies have reported the involvement of ferroptosis in the pathogenesis of septic cardiomyopathy. SGLT2 inhibitors such...
-
Article
Feasibility study on fruit parameter estimation based on hyperspectral LiDAR point cloud
Fruit parameter estimation is beneficial to intelligent management of orchards. This study proposed a compound method to estimate the fruit ripeness, number and size based on hyperspectral three-dimensional (3...
-
Article
Open AccessYoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission
Segmental bone defects, arising from factors such as trauma, tumor resection, and congenital malformations, present significant clinical challenges that often necessitate complex reconstruction strategies. Hyd...
-
Article
Enantioselective alkene hydroalkylation overcoming heteroatom constraints via cobalt catalysis
Alkene hydroalkylation enables efficient and selective formation of C(sp3)–C(sp3) bonds with unique advantages, such as exceptional chemoselectivity and remarkable tolerance of functional groups. However, elimina...
-
Article
Three-dimensional saturated C(sp3)-rich bioisosteres for benzene
Benzenes, the most ubiquitous structural moiety in marketed small-molecule drugs, are frequently associated with poor ‘drug-like’ properties, including metabolic instability, and poor aqueous solubility. In an...
-
Article
Effective Electrochemical Nitrogen Reduction through π Back-donation Process in Mn3+ of Mn-doped g-C3N4
Ammonia (NH3) synthesis via nitrogen reduction reaction under mild conditions is challenging due to the difficulty of activating nitrogen. Herein, Mn-doped g-C3N4 (x-Mn-CN, x = 5, 10, and 15) catalysts with effic...
-
Article
Upcycling waste sewage sludge into superior single-atom Fenton-like catalyst for sustainable water purification
The worldwide generation of waste sludge emanating from municipal wastewater treatment plants amounts to 80–90 million tons of dry matter annually and continues to escalate, posing a substantial economic and e...
-
Article
Engineering miniature IscB nickase for robust base editing with broad targeting range
IscB has a similar domain organization to Cas9, but the small size of IscB is better suited for delivery by adeno-associated virus. To improve the low editing efficiency of OgeuIscB (IscB from human gut metage...
-
Article
Cost-reduction implicit exponential Runge–Kutta methods for highly oscillatory systems
In this paper, two novel classes of implicit exponential Runge–Kutta (ERK) methods are studied for solving highly oscillatory systems. First of all, symplectic conditions for two kinds of exponential integrato...
-
Article
Novel ZIFs nanostructures electro-engineered at carbon fiber for the highly sensitive and selective detection of isoeugenol
Novel zeolitic imidazolate frameworks (ZIFs), classical subtypes of metal organic frameworks (MOFs), and nanostructures are electro-engineered onto carbon fiber (CF), leading to a unique freestanding electroch...
-
Article
Investigating the Influence of Weight Ratios of Polyester Fibers as an Adhesive on Mechanical and Acoustic Properties of Glass Fiber Composite Felts
This paper introduces glass/polyester fiber composite felts (GPCFs) to expand the application of glass fiber felt in composite fields, for satisfying the lightweight, high strength and excellent acoustic requi...
-
Article
Open AccessNeuroimmune modulating and energy supporting nanozyme-mimic scaffold synergistically promotes axon regeneration after spinal cord injury
Spinal cord injury (SCI) represents a profound central nervous system affliction, resulting in irreversibly compromised daily activities and disabilities. SCI involves excessive inflammatory responses, which a...
-
Article
Ultrasound-electrochemistry assisted liquid-phase co-exfoliation of phosphorene decorated by Au−Ag bimetallic nanoparticles as nanozyme for smartphone-based portable sensing of 4-nitrophenol
The stability of black phosphorene (BP) and its preparation and modification for develo** and applying devices have become a hot topic in the interdisciplinary field. We propose ultrasound-electrochemistry c...
-
Article
Correction: Correlations of FCGR2A 131R/H and FCGR3A 158V/F Polymorphisms with the Susceptibility of Peri-implantitis in Chinese Han Population
-
Article
A selenium-mediated layer-by-layer synthetic strategy for multilayered multicomponent nanocrystals
Ordered heterostructured nanocrystals with large compositional and morphological diversity are important for many applications. However, design of multicomponent nanostructures at the atomic level is difficult...
-
Article
Rapid degradation of thermosetting ester epoxies and monomer recovery methods
The degradation and recycling of waste epoxy resins is an urgent environmental problem, encouraging the use of degradable thermosetting epoxies. In this study, a high-performance thermosetting epoxy resin mate...
-
Article
PfAgo-based dual signal amplification biosensor for rapid and highly sensitive detection of alkaline phosphatase activity
A Pyrococcus furiosus Argonaute (PfAgo)-based biosensor is presented for alkaline phosphatase (ALP) activity detection in which the ALP-catalyzed hydrolysis of 3′-phosphate-modified functional DNA activates the s...
-
Article
Electrochemical Behavior of Pb(II) in NaCl–KCl Molten Salts
The electrochemical behavior of PbCl2 in NaCl–KCl molten salt on graphite and molybdenum electrodes was investigated using cyclic voltammetry, square wave voltammetry, chronopotentiometry, and open circuit chrono...
-
Article
Comprehensive Bioinformatics Analysis and Machine Learning of TTK as a Transhepatic Arterial Chemoembolization Resistance Target in Hepatocellular Carcinoma
Transhepatic arterial chemoembolization (TACE) is the standard treatment for intermediate-stage hepatocellular carcinoma (HCC). However, a significant proportion of patients are non-responders or poor responde...
-
Article
Fluorinated and sulfurized solid-electrolyte interface enabling durable and fast-charging graphite/LiFePO4 pouch batteries
Safe and fast charging is important for graphite/lithium iron phosphate (Gr/LFP) batteries in the fast-growing electric vehicle industry. However, conventional carbonate-based electrolytes produce an obstructi...
