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  1. Article

    Open Access

    The construction and use of bacterial DNA microarrays based on an optimized two-stage PCR strategy

    DNA microarrays are a powerful tool with important applications such as global gene expression profiling. Construction of bacterial DNA microarrays from genomic sequence data using a two-stage PCR amplificatio...

    Bradley L Postier, Hong-Liang Wang, Abhay Singh, Lori Impson in BMC Genomics (2003)

  2. Article

    Expression and functional analysis of the rice plasma-membrane intrinsic protein gene family

    Plasma membrane intrinsic proteins (PIPs) are a subfamily of aquaporins that enable fast and controlled translocation of water across the membrane. In this study, we systematically identified and cloned ten PIP g...

    Lei Guo, Zi Yi Wang, Hong Lin, Wei Er Cui, Jun Chen, Meihua Liu in Cell Research (2006)

  3. Article

    Open Access

    In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans

    Currently available vaccines against leptospirosis are of low efficacy, have an unacceptable side-effect profile, do not induce long-term protection, and provide no cross-protection against the different serov...

    Hong-Liang Yang, Yong-Zhang Zhu, **-Hong Qin, ** He, Xu-Cheng Jiang in BMC Genomics (2006)

  4. Article

    AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana

    Thiamine (vitamin B1) is an essential compound for organisms. It contains a pyrimidine ring structure and a thiazole ring structure. These two moieties of thiamine are synthesized independently and then coupled t...

    Danyu Kong, Yuxing Zhu, Huilan Wu, Xudong Cheng, Hui Liang, Hong-Qing Ling in Cell Research (2008)

  5. Article

    GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth

    Here, we report the identification of GIDE, a mitochondrially located E3 ubiquitin ligase. GIDE contains a C-terminal RING finger domain, which is mostly conserved with those of the IAP family members and is r...

    Bicheng Zhang, Jun Huang, Hong-Liang Li, Ting Liu, Yan-Yi Wang in Cell Research (2008)

  6. Article

    Velleratretraol, an unusual highly functionalized lactarane sesquiterpene from Lactarius vellereus

    An unusual highly functionalized lactarane sesquiterpene, named velleratretraol (1), was isolated from the ethanol extract of the fruiting body of the mushroom Lactarius vellereus. Its structure was determined th...

    Du-Qiang Luo, Li-Yan Zhao, Yao-Long Shi, Hong-Liang Tang in The Journal of Antibiotics (2009)

  7. Article

    Open Access

    Identification and functional characterization of small non-coding RNAs in Xanthomonas oryzae pathovar oryzae

    Small non-coding RNAs (sRNAs) are regarded as important regulators in prokaryotes and play essential roles in diverse cellular processes. Xanthomonas oryzae pathovar oryzae (Xoo) is an important plant pathogenic ...

    Hong Liang, Ying-Tao Zhao, Jie-Qiong Zhang, **u-Jie Wang, Rong-**ang Fang in BMC Genomics (2011)

  8. Article

    Conformational conversion and prion disease

    Liang Shen, Hong-Fang Ji in Nature Reviews Molecular Cell Biology (2011)

  9. Article

    Open Access

    Hypoxia-mimetic agents inhibit proliferation and alter the morphology of human umbilical cord-derived mesenchymal stem cells

    The therapeutic efficacy of human mesenchymal stem cells (hMSCs) for the treatment of hypoxic-ischemic diseases is closely related to level of hypoxia in the damaged tissues. To elucidate the potential therape...

    Hui-Lan Zeng, Qi Zhong, Yong-Liang Qin, Qian-Qian Bu, **n-Ai Han in BMC Cell Biology (2011)

  10. Article

    Open Access

    Expansion and diversification of the SET domain gene family following whole-genome duplications in Populus trichocarpa

    Histone lysine methylation modifies chromatin structure and regulates eukaryotic gene transcription and a variety of developmental and physiological processes. SET domain proteins are lysine methyltransferases...

    Li Lei, Shi-Liang Zhou, Hong Ma, Liang-Sheng Zhang in BMC Evolutionary Biology (2012)

  11. Article

    Piglets cloned from induced pluripotent stem cells

    Nana Fan, Jijun Chen, Zhouchun Shang, Hongwei Dou, Guangzhen Ji in Cell Research (2013)

  12. Article

    Open Access

    The genome- and transcriptome-wide analysis of innate immunity in the brown planthopper, Nilaparvata lugens

    The brown planthopper (Nilaparvata lugens) is one of the most serious rice plant pests in Asia. N. lugens causes extensive rice damage by sucking rice phloem sap, which results in stunted plant growth and the tra...

    Yan-Yuan Bao, Lv-Yu Qu, Dong Zhao, Li-Bo Chen, Hong-Yuan **, Liang-Min Xu in BMC Genomics (2013)

  13. Article

    Open Access

    Global transcriptome profiles of Camellia sinensis during cold acclimation

    Tea is the most popular non-alcoholic health beverage in the world. The tea plant (Camellia sinensis (L.) O. Kuntze) needs to undergo a cold acclimation process to enhance its freezing tolerance in winter. Change...

    **n-Chao Wang, Qiong-Yi Zhao, Chun-Lei Ma, Zong-Hong Zhang, Hong-Li Cao in BMC Genomics (2013)

  14. Article

    Open Access

    Comparative transcriptome analysis of tomato (Solanum lycopersicum) in response to exogenous abscisic acid

    Abscisic acid (ABA) can regulate the expressions of many stress-responsive genes in plants. However, in defense responses to pathogens, mounting evidence suggests that ABA plays variable roles. Little informat...

    Yan Wang, **ang Tao, **ao-Mei Tang, Liang **ao, Jiao-long Sun, Xue-Feng Yan in BMC Genomics (2013)

  15. Article

    Molecular cloning, genomic structure, polymorphism and expression analysis of major histocompatibility complex class IIA gene of swamp eel Monopterus albus

    Major histocompatibility complex (MHC) class II molecules play an important role in the immune response of vertebrates. In this paper, full-length MHC IIA cDNA was isolated from swamp eel (Monopterus albus) by ra...

    Wei Li, Wen-xiu Sun, Liang Meng, Deng-wei Hong in Biologia (2014)

  16. Article

    Open Access

    A phylogeny for the pomatiopsidae (Gastropoda: Rissooidea): a resource for taxonomic, parasitological and biodiversity studies

    The Pomatiopsidae are reported from northern India into southern China and Southeast Asia, with two sub-families, the Pomatiopsinae (which include freshwater, amphibious, terrestrial and marine species) and th...

    Liang Liu, Guan-Nan Huo, Hong-Bin He, Benjiang Zhou in BMC Evolutionary Biology (2014)

  17. Article

    Open Access

    Sequence analysis of mitochondrial ND1 gene can reveal the genetic structure and origin of Bactrocera dorsalis s.s.

    The oriental fruit fly, Bactrocera dorsalis s.s., is one of the most important quarantine pests in many countries, including China. Although the oriental fruit fly has been investigated extensively, its origins a...

    Zhong-Zhen Wu, Hong-Mei Li, Shu-Ying Bin, Jun Ma, Hua-Liang He in BMC Evolutionary Biology (2014)

  18. Article

    Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy

    Pathological cardiac hypertrophy is an inevitable forerunner of heart failure. Regardless of the etiology of cardiac hypertrophy, cardiomyocyte mitochondrial alterations are always observed in this context. Th...

    Jun Li, Man Qi, Changming Li, Dan Shi, Dasheng Zhang, Duanyang **e in Cell Research (2014)

  19. Article

    Open Access

    The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes

    The tyrosine phosphorylation barcode encoded in C-terminus of HER2 and its ubiquitination regulate diverse HER2 functions. PTPN18 was reported as a HER2 phosphatase; however, the exact mechanism by which it de...

    Hong-Mei Wang, Yun-Fei Xu, Shang-Lei Ning, Du-**ao Yang, Yi Li, Yu-Jie Du in Cell Research (2014)

  20. Article

    Open Access

    Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

    Protein misfolding and aggregation as a consequence of impaired protein homeostasis (proteostasis) not only characterizes numerous age-related diseases but also the aging process itself. Functionally related t...

    Vanessa Liang, Milena Ullrich, Hong Lam in Cellular and Molecular Life Sciences (2014)

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