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    Article

    Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

    The clinical translation of cationic α-helical antimicrobial peptides (AMPs) has been hindered by structural instability, proteolytic degradation and in vivo toxicity from nonspecific membrane lysis. Although ...

    Rida Mourtada, Henry D. Herce, Daniel J. Yin, Jamie A. Moroco in Nature Biotechnology (2019)

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    Protocol

    Visualization of the Nucleolus in Living Cells with Cell-Penetrating Fluorescent Peptides

    The nucleolus is the hallmark of nuclear compartmentalization and has been shown to exert multiple roles in cellular metabolism besides its main function as the place of ribosomal RNA synthesis and assembly of...

    Robert M. Martin, Henry D. Herce, Anne K. Ludwig, M. Cristina Cardoso in The Nucleolus (2016)