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  1. No Access

    Article

    A SPH-lattice spring method for modelling Fluid Structure Interaction involving composite body and free surface

    In this paper, a 3D particle-based Fluid Structure Interaction (FSI) solver based on Smoothed Particle Hydrodynamics (SPH) for fluid modelling and Volume-Compensated Particle Method (VCPM) (or known as Lattice...

    W. C. Low, K. C. Ng, H. K. Ng in Computational Particle Mechanics (2023)

  2. No Access

    Chapter

    Investigation of Pyrolysis Parameters on the Yield and Quality of Bio-Oil from Jatropha curcas Wastes

    Jatropha curcas pressed cake leftover after oil extraction for biodiesel production is considered as waste. Following physicochemical characterisation tests, this biomass waste was pyrolysed over a...

    S. A. Jourabchi, S. Gan, H. K. Ng in Developments in Sustainable Chemical and B… (2013)

  3. No Access

    Article

    Hypertensive choroidopathy in Castleman's disease

    David T. L. Liu, Jerry A. Shields, C. L. Li in Graefe's Archive for Clinical and Experime… (2011)

  4. Article

    Notch signaling and ghost cell fate in the calcifying cystig odontogenic tumor

    Notch signaling is an evolutionarily conserved mechanism that enables adjacent cells to adopt different fates. Ghost cells (GCs) are anucleate cells with homogeneous pale eosinophilic cytoplasm and very pale t...

    C. H. Siar, T. Kawakami, R. R. Buery, K. Nakano in European Journal of Medical Research (2011)

  5. No Access

    Article

    Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion

    Minichromosome maintenance (MCM) proteins 2–7 are important in DNA replication licensing. Functional roles beyond licensing are speculated. In addition, significances in medulloblastoma (MB) remain unclear. In...

    K-M Lau, Q K Y Chan, J C S Pang, K K W Li, W W Yeung, N Y F Chung, P C Lui in Oncogene (2010)

  6. Article

    Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G2 cell-cycle arrest

    G-protein-coupled receptor-30 (GPR30) shows estrogen-binding affinity and mediates non-genomic signaling of estrogen to regulate cell growth. We here showed for the first time, in contrast to the reported prom...

    Q K Y Chan, H-M Lam, C-F Ng, A Y Y Lee, E S Y Chan, H-K Ng in Cell Death & Differentiation (2010)

  7. No Access

    Chapter and Conference Paper

    Simulating the C2SM ‘Fast’ Robot

    A critical problem in the deployment of commercial teleoperated robots is the development of effective training tools and methodologies. This paper describes our approach to the problem of providing such train...

    R. Codd-Downey, M. Jenkin, M. Ansell in Simulation, Modeling, and Programming for … (2010)

  8. No Access

    Article

    Pancreatic islet β-cell deficit and glucose intolerance in rats with uninephrectomy

    This study was performed to examine the effect of chronic renal impairment and renin-angiotensin system (RAS) activation induced by unilateral nephrectomy (UNX) on the development of pancreatic islet β-cell de...

    Y. Sui, H.-L. Zhao, R. C. W. Ma, C. S. Ho in Cellular and Molecular Life Sciences (2007)

  9. No Access

    Chapter

    Migration of bone marrow stem cells in ischaemic brain

    Stem cell therapy has been demonstrated to be effective in the management of haematological malignancy and solid cancer, but its role in neurodegenerative conditions remains uncertain. We hypothesize that: (1)...

    W. S. Poon, G. Lu, K. S. Tsang, X. L. Zhu in Advances in Functional and Reparative Neur… (2006)

  10. No Access

    Article

    Differential role of hydrogen peroxide and staurosporine in induction of cell death in glioblastoma cells lacking DNA-dependent protein kinase

    Various DNA double-strand break repair mechanisms, in which DNA-dependent protein kinase (DNA-PK) has a major role, are involved both in the development and treatment of glioblastoma. The aim of the present st...

    G. G. Chen, F. L. F. Sin, B. C. S. Leung, H. K. Ng, W. S. Poon in Apoptosis (2005)

  11. Article

    Open Access

    Identification of two contiguous minimally deleted regions on chromosome 1p36.31–p36.32 in oligodendroglial tumours

    Loss of the short arm of chromosome 1 is a hallmark of oligodendroglial tumours (OTs). Deletion map** studies in OTs have revealed multiple commonly deleted regions on chromosome 1p, suggesting that there ar...

    Z Dong, JC-S Pang, M H Ng, W S Poon, L Zhou, H-K Ng in British Journal of Cancer (2004)

  12. Article

    The use of autologous serum tears in persistent corneal epithelial defects

    Purpose Persistent corneal epithelial defects (PED) present a very challenging problem to anterior segment surgeons. Autologous serum tears had been demonstrated to be beneficial in the treatment of PED. The curr...

    A L Young, A C O Cheng, H K Ng, L L Cheng, G Y S Leung, D S C Lam in Eye (2004)

  13. Article

    Open Access

    High-resolution genome-wide allelotype analysis identifies loss of chromosome 14q as a recurrent genetic alteration in astrocytic tumours

    Diffusely infiltrative astrocytic tumours are the most common neoplasms in the human brain. To localise putative tumour suppressor loci that are involved in low-grade astrocytomas, we performed high-resolution...

    J Hu, JC-s Pang, CY-k Tong, B Lau, X-l Yin, W-S Poon in British Journal of Cancer (2002)

  14. Article

    Open Access

    Antisense epidermal growth factor receptor RNA transfection in human glioblastoma cells down-regulates telomerase activity and telomere length

    Epidermal growth factor receptor is overexpressed and/or amplified in up to 50% of glioblastomas, suggesting an important role of this gene in glial tumorigenesis and progression. In the present study we demon...

    X-X Tian, J C-S Pang, J Zheng, J Chen, S S T To, H-K Ng in British Journal of Cancer (2002)

  15. No Access

    Article

    Epithelioid haemangioendothelioma of the brain: a case report

    We report a rare epithelioid haemangioendothelioma in the frontal lobe. The CT and MRI findings are characteristic and correspond to histological features intermediate between those a cavernous haemangioma an...

    Y. L. Chan, H. K. Ng, W. S. Poon, H. S. Cheung in Neuroradiology (2001)

  16. No Access

    Chapter and Conference Paper

    The Impact of Acute Hyponatraemia on Severe Traumatic Brain Injury in Rats

    The effect of experimental acute hyponatraemia on severe traumatic brain injury (TBI) was studied in a modified impact-acceleration model. The cortical contusional volume was quantified by image analysis on se...

    C. Ke, Dr. W. S. Poon, H. K. Ng, N. L. S. Tang, Y. Chan, J. Y. Wang in Brain Edema XI (2000)

  17. Article

    Open Access

    Altered expression of the suppressors PML and p53 in glioblastoma cells with the antisense-EGF-receptor

    Gene amplification and enhanced expression of the epidermal growth factor receptor (EGFR) represent the major molecular genetic alteration in glioblastomas and it may play an essential role in cell growth and ...

    X X Tian, J Y H Chan, J C S Pang, J Chen, J H He, T S S To in British Journal of Cancer (1999)

  18. No Access

    Article

    MRI demonstration of subarachnoid neurocysticercosis simulating metastatic disease

    We present a patient with neurocysticercosis with spinal subarachnoid spread who presented with lower back pain and progressive numbness and weakness of the left leg. MRI of the spine simulated metastasis. MR...

    K. Y. Lau, D. J. Roebuck, V. Mok, H. K. Ng, J. Lam, J. G. C. Teo, R. Kay in Neuroradiology (1998)

  19. No Access

    Article

    The time course and regional variations of lipid peroxidation after diffuse brain injury in rats

    Free radicals are generated after head injury. These radicals rapidly react with polyunsaturated fatty acids in the cell membrane and cause membrane destruction. This process is called lipid per-oxidation. Mal...

    J. N. K. Hsiang, J. Y. Wang, S. -M. Ip, H. -K. Ng, A. Stadlin in Acta Neurochirurgica (1997)

  20. No Access

    Article

    Magneto-Optic Studies of GaN Films and GaN/AlGaN Heterostructures

    Magneto-studies have been carried out for several MOCVD grown GaN thin films and GaN/AlGaN heterostructures at magnetic fields up to 30 T and at temperatures between 4.2 K to 100 K. Electron cyclotron resonanc...

    Y.J. Wang, H.K. Ng, R. Kaplan, K. Doverspike in MRS Online Proceedings Library (1995)

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